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Tixagevimab

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Catalog No. T76976Cas No. 2420564-02-7
Alias AZD8895, AZD 8895

Tixagevimab (AZD8895) is a humanized monoclonal antibody targeting the spike protein of SARS-CoV-2, with antiviral activity. It works by binding to the RBD and S protein domain, blocking the interaction with receptors.

Tixagevimab

Tixagevimab

😃Good
Catalog No. T76976Alias AZD8895, AZD 8895Cas No. 2420564-02-7
Tixagevimab (AZD8895) is a humanized monoclonal antibody targeting the spike protein of SARS-CoV-2, with antiviral activity. It works by binding to the RBD and S protein domain, blocking the interaction with receptors.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$247In StockIn Stock
5 mg$645In StockIn Stock
10 mg$987-In Stock
25 mg$1,530-In Stock
50 mg$1,980-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:100% (SEC-HPLC)
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Product Introduction

Bioactivity
Description
Tixagevimab (AZD8895) is a humanized monoclonal antibody targeting the spike protein of SARS-CoV-2, with antiviral activity. It works by binding to the RBD and S protein domain, blocking the interaction with receptors.
In vivo
Tixagevimab can be combined with Cilgavimab to form AZD7442, AZD7442 (2,4 or 16 mg/kg, intravenously) in hamsters infected with the G61 strain and Omicron variant, resulted in a dose-dependent decrease in lung infection titers and viral RNA levels in hamsters, and the infection titer at 16 mg/kg was significantly lower than that at 2 mg/kg. [1]
SynonymsAZD8895, AZD 8895
Reactivity
Virus
Application
Functional assay
Antibody Type
Monoclonal
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetSpike RBD
Chemical Properties
Molecular Weight146.48 kDa
Cas No.2420564-02-7
ColorTransparent
AppearanceLiquid
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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