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Tixagevimab
(Synonyms: AZD8895, AZD 8895) Copy Product Info
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Synonyms: AZD8895, AZD 8895
Catalog No. T76976 Copy Product Info
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Tixagevimab (AZD8895) is a humanized monoclonal antibody targeting the spike protein of SARS-CoV-2, with antiviral activity. It works by binding to the RBD and S protein domain, blocking the interaction with receptors.
Cas No. 2420564-02-7
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $247 | In Stock | In Stock | |
| 5 mg | $645 | In Stock | In Stock | |
| 10 mg | $987 | - | In Stock | |
| 25 mg | $1,530 | - | In Stock | |
| 50 mg | $1,980 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:100% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Tixagevimab (AZD8895) is a humanized monoclonal antibody targeting the spike protein of SARS-CoV-2, with antiviral activity. It works by binding to the RBD and S protein domain, blocking the interaction with receptors. |
| In vivo | Tixagevimab can be combined with Cilgavimab to form AZD7442, AZD7442 (2,4 or 16 mg/kg, intravenously) in hamsters infected with the G61 strain and Omicron variant, resulted in a dose-dependent decrease in lung infection titers and viral RNA levels in hamsters, and the infection titer at 16 mg/kg was significantly lower than that at 2 mg/kg. [1] |
| Synonyms | AZD8895, AZD 8895 |
| Reactivity | Virus |
| Verified Activity | Immobilized SARS-CoV-2 Spike RBD Protein (His) (TMPY-05668) at 1 μg/mL (100 μL/well) can bind Tixagevimab. The EC50 is 0.98 ng/mL. |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | Spike RBD |
| Molecular Weight | 146.48 kDa |
| Cas No. | 2420564-02-7 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Tixagevimab chemical structure | Tixagevimab in vivo | Tixagevimab molecular weight
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