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Tixagevimab (Synonyms: AZD8895, AZD 8895)

Catalog No. T76976 Copy Product Info
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Tixagevimab (AZD8895) is a humanized monoclonal antibody targeting the spike protein of SARS-CoV-2, with antiviral activity. It works by binding to the RBD and S protein domain, blocking the interaction with receptors.

Tixagevimab

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Catalog No. T76976
Synonyms AZD8895, AZD 8895

Tixagevimab (AZD8895) is a humanized monoclonal antibody targeting the spike protein of SARS-CoV-2, with antiviral activity. It works by binding to the RBD and S protein domain, blocking the interaction with receptors.

Tixagevimab
Cas No. 2420564-02-7
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$247In StockIn Stock
5 mg$645In StockIn Stock
10 mg$987-In Stock
25 mg$1,530-In Stock
50 mg$1,980-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:100% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Tixagevimab (AZD8895) is a humanized monoclonal antibody targeting the spike protein of SARS-CoV-2, with antiviral activity. It works by binding to the RBD and S protein domain, blocking the interaction with receptors.
In vivo
Tixagevimab can be combined with Cilgavimab to form AZD7442, AZD7442 (2,4 or 16 mg/kg, intravenously) in hamsters infected with the G61 strain and Omicron variant, resulted in a dose-dependent decrease in lung infection titers and viral RNA levels in hamsters, and the infection titer at 16 mg/kg was significantly lower than that at 2 mg/kg. [1]
SynonymsAZD8895, AZD 8895
Reactivity
Virus
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetSpike RBD
Chemical Properties
Molecular Weight146.48 kDa
Cas No.2420564-02-7
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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