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Anti-BTK Antibody (6Q257)

Catalog No. TMAC-00486 Copy Product Info
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Anti-BTK Antibody (6Q257) is a Rabbit antibody targeting BTK. Anti-BTK Antibody (6Q257) can be used in IP,WB.

Anti-BTK Antibody (6Q257)

Copy Product Info
🥰Excellent
Catalog No. TMAC-00486

Anti-BTK Antibody (6Q257) is a Rabbit antibody targeting BTK. Anti-BTK Antibody (6Q257) can be used in IP,WB.

Anti-BTK Antibody
(6Q257)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-BTK Antibody (6Q257) is a Rabbit antibody targeting BTK. Anti-BTK Antibody (6Q257) can be used in IP,WB.
Ig Type
IgG
Clone
6Q257
Reactivity
Human
Verified Activity
1. Western blot analysis of BTK on Raji cells lysates using anti-BTK antibody at 1/1,000 dilution.
verifiedActivity
Application
Recommended Dose
WB: 1:1000-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe Tec family of non-receptor tyrosine kinases is composed of six proteins designated Tec, Emt (also known as Itk or Tsk), Btk (previously known as Atk, BPK or Emb), Bmx, Txk (also known as Rlk) and Dsrc28C. All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini. Four alternatively spliced forms of Tec are found to be expressed broadly in cells of hematopoietic lineage and hepatocytes. The Emt gene product associates with CD28 and becomes activated subsequent to CD28 ligation. Btk is necessary for proper B cell development, and mutations in the gene encoding Btk have been associated with families suffering from X-linked agammaglobulinemia, also referred to as Bruton's disease. The Bmx protein shares a high degree of homology with Btk and seems to be expressed at highest levels in the heart. Txk expression is T cell-specific, while expression of the Drosophila Tec homolog, Dsrc28C, is developmentally regulated.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 76 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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