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Gemcabene calcium

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Catalog No. T11386Cas No. 209789-08-2
Alias PD-72953 calcium

Gemcabene calcium , a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) andexerting anti-inflammatory activity, lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP).

Gemcabene calcium
Other Forms of Gemcabene calcium:
GemcabeneT11386L183293-82-5
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Gemcabene calcium

😃Good
Catalog No. T11386Alias PD-72953 calciumCas No. 209789-08-2
Gemcabene calcium , a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) andexerting anti-inflammatory activity, lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$835 days5 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
Gemcabene calcium , a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) andexerting anti-inflammatory activity, lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP).
In vitro
Gemcabene calcium (PD-72953 calcium) effectively reduces hepatic mRNA levels associated with inflammation (TNF-α, MCP-1, MIP-1β, CCR5, CCR2, NF-κB), fibrosis (TIMP-1, MMP-2), and fat production and regulation processes (ApoC-III, ACC1, ADH-4, Sulf-2).
SynonymsPD-72953 calcium
Chemical Properties
Molecular Weight344.505
FormulaC16H32CaO5
Cas No.209789-08-2
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 10 mg/mL (29.03 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM2.9027 mL14.5136 mL29.0272 mL145.1358 mL
5 mM0.5805 mL2.9027 mL5.8054 mL29.0272 mL
10 mM0.2903 mL1.4514 mL2.9027 mL14.5136 mL
20 mM0.1451 mL0.7257 mL1.4514 mL7.2568 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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Keywords

Gemcabene calcium
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