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Anti-ABL2 Antibody (4X240) is a Rabbit antibody targeting ABL2. Anti-ABL2 Antibody (4X240) can be used in WB,FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $297 | 7-10 days | |
100 μL | $498 | 7-10 days |
Description | Anti-ABL2 Antibody (4X240) is a Rabbit antibody targeting ABL2. Anti-ABL2 Antibody (4X240) can be used in WB,FCM. |
Synonyms | v abl Abelson murine leukemia viral oncogene homolog 2, Tyrosine-protein kinase ARG, Tyrosine protein kinase ABL2, Tyrosine kinase ARG, ARG, ABLL, ABL2_HUMAN, ABL 2, Abelson-related gene protein, Abelson tyrosine-protein kinase 2, Abelson related gene protein, Abelson murine leukemia viral oncogene homolog 2 |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat |
Verified Activity | 1. Western blot analysis of ABL2 on different lysates using anti-ABL2 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: PC-12, Lane 3: Jurkat. 2. Flow cytometric analysis of Raji cells with ABL2 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
Application | |
Recommended Dose | WB: 1:1000-2000; FCM: 1:50-100 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | Recombinant Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | The Abl oncogene was initially identified as the viral transforming gene of Abelson murine leukemia virus (A-MuLV). The major translational product of c-Abl has been identified as a protein with tyrosine kinase activity and an SH2 domain. The Abl oncogene is implicated in several human leukemias including chronic myelocytic leukemia (CML), in which it undergoes a (9;22) chromosomal translocation and produces the Philadelphia (Ph1) chromosome. The molecular consequence of this translocation is the generation of a chimeric Bcr/c-Abl mRNA encoding activated Abl protein tyrosine kinase. The related protein tyrosine kinase Arg, also designated Abl2, contains an SH2 and an SH3 domain. Arg has been shown to interact with and to phosphorylate c-Crk. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 128 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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