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Anti-RAB8A Monoclonal Antibody (1T67)

(Synonyms: RAB8, MEL) Copy Product Info
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Synonyms: RAB8, MEL

Catalog No. TMAC-03486 Copy Product Info
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Anti-RAB8A Monoclonal Antibody (1T67) is a Mouse antibody targeting RAB8A. Anti-RAB8A Monoclonal Antibody (1T67) can be used in FCM.

Anti-RAB8A Monoclonal Antibody
(1T67)

Pack SizePriceUSA StockGlobal StockQuantity
50 µL$2987-10 days7-10 days
100 µL$4267-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-RAB8A Monoclonal Antibody (1T67) is a Mouse antibody targeting RAB8A. Anti-RAB8A Monoclonal Antibody (1T67) can be used in FCM.
SynonymsRAB8, MEL
Ig Type
IgG2b
Clone
1T67
Reactivity
Human
Verified Activity
Flow cytometric analysis of Hela cells with Rab8 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
Anti-RAB8A Monoclonal Antibody (1T67)
Application
Recommended Dose
FCM: 1/200-1/400
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationPurified by protein A or protein G
AppearanceLiquid
FormulationPBS with 0.05% sodium azide
Concentration1 mg/mL
Research BackgroundThe protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Purified recombinant fragment of human Rab8 (AA: 68-207) expressed in E. Coli.
Antigen Species
Human
Gene Name
RAB8A
Gene ID
Protein Name
Ras-related protein Rab-8A
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 24 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: Anti-RAB8A Monoclonal Antibody (1T67) molecular weight