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Anti-NR1D1 Antibody (2D57)
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Catalog No. TMAC-02888
Alias V-erbA-related protein 1, Thyroid hormone receptor, alpha-1- like, Thyroid hormone receptor, alpha like, THRAL, THRA1, Rev-erbA-alpha, Rev-ErbAalpha, Reverba, Rev erbalpha, Rev erbAalpha, Nuclear receptor subfamily 1 group D member 1, Nuclear receptor Rev ErbA alpha, NR1D1_HUMAN, Nr1d1, hRev, ERBA-related 1, EAR-1, EAR1
Anti-NR1D1 Antibody (2D57) is a Rabbit antibody targeting NR1D1. Anti-NR1D1 Antibody (2D57) can be used in WB,IHC.
Anti-NR1D1 Antibody (2D57)
Anti-NR1D1 Antibody (2D57)
😃Good
Catalog No. TMAC-02888Alias V-erbA-related protein 1, Thyroid hormone receptor, alpha-1- like, Thyroid hormone receptor, alpha like, THRAL, THRA1, Rev-erbA-alpha, Rev-ErbAalpha, Reverba, Rev erbalpha, Rev erbAalpha, Nuclear receptor subfamily 1 group D member 1, Nuclear receptor Rev ErbA alpha, NR1D1_HUMAN, Nr1d1, hRev, ERBA-related 1, EAR-1, EAR1
Anti-NR1D1 Antibody (2D57) is a Rabbit antibody targeting NR1D1. Anti-NR1D1 Antibody (2D57) can be used in WB,IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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Chemical Properties
| Description | Anti-NR1D1 Antibody (2D57) is a Rabbit antibody targeting NR1D1. Anti-NR1D1 Antibody (2D57) can be used in WB,IHC. |
| Synonyms | V-erbA-related protein 1, Thyroid hormone receptor, alpha-1- like, Thyroid hormone receptor, alpha like, THRAL, THRA1, Rev-erbA-alpha, Rev-ErbAalpha, Reverba, Rev erbalpha, Rev erbAalpha, Nuclear receptor subfamily 1 group D member 1, Nuclear receptor Rev ErbA alpha, NR1D1_HUMAN, Nr1d1, hRev, ERBA-related 1, EAR-1, EAR1 |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of NR1D1 on HepG2 and SiHa cell lysates using anti-NR1D1 antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-NR1D1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-NR1D1 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse fallopian tubes using anti-NR1D1 antibody. Counter stained with hematoxylin. |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex transcription machinery that governs circadian rhythmicity and forms a critical negative limb of the circadian clock by directly repressing the expression of core clock components ARTNL/BMAL1, CLOCK and CRY1. Also regulates genes involved in metabolic functions, including lipid and bile acid metabolism, adipogenesis, gluconeogenesis and the macrophage inflammatory response. Acts as a receptor for heme which stimulates its interaction with the NCOR1/HDAC3 corepressor complex, enhancing transcriptional repression. Recognizes two classes of DNA response elements within the promoter of its target genes and can bind to DNA as either monomers or homodimers, depending on the nature of the response element. Binds as a monomer to a response element composed of the consensus half-site motif 5'-[A/G]GGTCA-3' preceded by an A/T-rich 5' sequence (RevRE), or as a homodimer to a direct repeat of the core motif spaced by two nucleotides (RevDR-2). |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 67 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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