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Anti-EGLN2 Antibody (7L776)

(Synonyms: Prolyl hydroxylase EGLN2, Prolyl hydroxylase domain-containing protein 1 (PHD1), Hypoxia-inducible factor prolyl hydroxylase 1 (HIF-PH1, HPH-3, HPH-1), HIF-prolyl hydroxylase 1, Estrogen-induced tag 6 (EIT-6), EIT6, EGLN2, Egl nine homolog 2) Copy Product Info
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Synonyms: Prolyl hydroxylase EGLN2, Prolyl hydroxylase domain-containing protein 1 (PHD1), Hypoxia-inducible factor prolyl hydroxylase 1 (HIF-PH1, HPH-3, HPH-1), HIF-prolyl hydroxylase 1, Estrogen-induced tag 6 (EIT-6), EIT6, EGLN2, Egl nine homolog 2

Catalog No. TMAC-03183 Copy Product Info
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Anti-EGLN2 Antibody (7L776) is a Rabbit antibody targeting EGLN2. Anti-EGLN2 Antibody (7L776) can be used in FCM,ICC/IF,IHC,WB.
Anti-EGLN2 Antibody
(7L776)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-EGLN2 Antibody (7L776) is a Rabbit antibody targeting EGLN2. Anti-EGLN2 Antibody (7L776) can be used in FCM,ICC/IF,IHC,WB.
SynonymsProlyl hydroxylase EGLN2, Prolyl hydroxylase domain-containing protein 1 (PHD1), Hypoxia-inducible factor prolyl hydroxylase 1 (HIF-PH1, HPH-3, HPH-1), HIF-prolyl hydroxylase 1, Estrogen-induced tag 6 (EIT-6), EIT6, EGLN2, Egl nine homolog 2
Ig Type
IgG
Clone
7L776
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundProlyl hydroxylase domain proteins HIF PHD1, HIF PHD2 and HIF PHD3 (known as PHD1, PHD2 and PHD3 in rodents, respectively) can hydroxylate HIF-α subunits. Hypoxia-inducible factor (HIF) is a transcriptional regulator important in several aspects of oxygen homeostasis. The prolyl hydroxylases catalyze the posttranslational formation of 4-hydroxyproline in HIF-α proteins. HIF PHD1, which is widely expressed, with highest levels of expression in testis, functions as a cellular oxygen sensor and is important in cell growth regulation. HIF PHD1 can localize to the nucleus or the cytoplasm and is also detected in hormone responsive tissues, such as normal and cancerous mammary, ovarian and prostate epithelium. HIF PHD1 is encoded by EGLN2, which maps to chromosome 19q13.3. HIF PHD2 is regarded as the main cellular oxygen sensor, as RNA interference against HIF PHD2, but not HIF PHD1 or HIF PHD3, is enough to stabilize HIF-1α in normoxia. HIF PHD2, a direct HIF target gene, is expressed mainly in skeletal muscle, heart, kidney and brain. HIF PHD3 may play a role in the regulation of cell growth in muscle cells and in apoptosis in neuronal tissue. HIF PHD3 is widely expressed, although the highest levels can be detected in placenta and he
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 44 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Related Tags: Anti-EGLN2 Antibody (7L776) molecular weight