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Anti-Ku70 Antibody (6Y615) (Synonyms: XRCC6_HUMAN, Xrcc6, XRCC 6, X-ray repair cross-complementing protein 6|...)

Catalog No. TMAC-02341 Copy Product Info
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Anti-Ku70 Antibody (6Y615) is a Rabbit antibody targeting Ku70. Anti-Ku70 Antibody (6Y615) can be used in FCM,ICC/IF,IHC,IP,WB.

Anti-Ku70 Antibody (6Y615)

Copy Product Info
🥰Excellent
Catalog No. TMAC-02341
Synonyms XRCC6_HUMAN, Xrcc6, XRCC 6, X-ray repair cross-complementing protein 6, X-ray repair complementing defective repair in Chinese hamster cells 6, X ray repair complementing defective repair in Chinese hamster cells 6, TLAA, Thyroid-lupus autoantigen, Thyroid lupus autoantigen p70, Thyroid lupus autoantigen, Thyroid autoantigen 70kD (Ku antigen), Thyroid autoantigen, ML8, Lupus Ku autoantigen protein p70, Kup70, Ku70 DNA binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa, Ku p70, Ku autoantigen, 70kDa, Ku autoantigen p70 subunit, Ku 70, G22P1, DNA repair protein XRCC6, CTCBF, CTC75, CTC box-binding factor 75 kDa subunit, CTC box binding factor 75 kDa subunit, ATP-dependent DNA helicase II 70 kDa subunit, ATP-dependent DNA helicase 2 subunit 1, ATP dependent DNA helicase II 70 kDa subunit, ATP dependent DNA helicase 2 subunit 1, 70 kDa subunit of Ku antigen, 5''-dRP lyase Ku70, 5''-deoxyribose-5-phosphate lyase Ku70

Anti-Ku70 Antibody (6Y615) is a Rabbit antibody targeting Ku70. Anti-Ku70 Antibody (6Y615) can be used in FCM,ICC/IF,IHC,IP,WB.

Anti-Ku70 Antibody
(6Y615)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Ku70 Antibody (6Y615) is a Rabbit antibody targeting Ku70. Anti-Ku70 Antibody (6Y615) can be used in FCM,ICC/IF,IHC,IP,WB.
SynonymsXRCC6_HUMAN, Xrcc6, XRCC 6, X-ray repair cross-complementing protein 6, X-ray repair complementing defective repair in Chinese hamster cells 6, X ray repair complementing defective repair in Chinese hamster cells 6, TLAA, Thyroid-lupus autoantigen, Thyroid lupus autoantigen p70, Thyroid lupus autoantigen, Thyroid autoantigen 70kD (Ku antigen), Thyroid autoantigen, ML8, Lupus Ku autoantigen protein p70, Kup70, Ku70 DNA binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa, Ku p70, Ku autoantigen, 70kDa, Ku autoantigen p70 subunit, Ku 70, G22P1, DNA repair protein XRCC6, CTCBF, CTC75, CTC box-binding factor 75 kDa subunit, CTC box binding factor 75 kDa subunit, ATP-dependent DNA helicase II 70 kDa subunit, ATP-dependent DNA helicase 2 subunit 1, ATP dependent DNA helicase II 70 kDa subunit, ATP dependent DNA helicase 2 subunit 1, 70 kDa subunit of Ku antigen, 5''-dRP lyase Ku70, 5''-deoxyribose-5-phosphate lyase Ku70
Ig Type
IgG
Clone
6Y615
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; ICC/IF: 1:50-200; IP: 1:10-50; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe Ku protein is localized in the nucleus and is composed of subunits referred to as Ku-70 (p70) and Ku-86 (p86) which is also known by the synonym Ku-80 or (p80). Ku was first described as an autoantigen to which antibodies were produced in a patient with scleroderma polymyositis overlap syndrome, and was later found in the sera of patients with other rheumatic diseases. Both subunits of the Ku protein have been cloned, and a number of functions have been proposed for Ku, including cell signaling, DNA replication and transcriptional activation. Ku is involved in Pol II-directed transcription by virtue of its DNA binding activity, serving as the regulatory component of the DNA-associated protein kinase that phosphorylates Pol II and transcription factor Sp. Ku proteins also activate transcription from the U1 small nuclear RNA and the human transferrin receptor gene promoters. A Ku-related protein designated the enhancer 1 binding factor (E1BF), composed of two subunits, has been identified as a positive regulator of RNA polymerase I transcription initiation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 70 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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