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Anti-Ku70 Antibody (6Y615)
😃Good
Catalog No. TMAC-02341
Alias XRCC6_HUMAN, Xrcc6, XRCC 6, X-ray repair cross-complementing protein 6, X-ray repair complementing defective repair in Chinese hamster cells 6, X ray repair complementing defective repair in Chinese hamster cells 6, TLAA, Thyroid-lupus autoantigen, Thyroid lupus autoantigen p70, Thyroid lupus autoantigen, Thyroid autoantigen 70kD (Ku antigen), Thyroid autoantigen, ML8, Lupus Ku autoantigen protein p70, Kup70, Ku70 DNA binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa, Ku p70, Ku autoantigen, 70kDa, Ku autoantigen p70 subunit, Ku 70, G22P1, DNA repair protein XRCC6, CTCBF, CTC75, CTC box-binding factor 75 kDa subunit, CTC box binding factor 75 kDa subunit, ATP-dependent DNA helicase II 70 kDa subunit, ATP-dependent DNA helicase 2 subunit 1, ATP dependent DNA helicase II 70 kDa subunit, ATP dependent DNA helicase 2 subunit 1, 70 kDa subunit of Ku antigen, 5''-dRP lyase Ku70, 5''-deoxyribose-5-phosphate lyase Ku70
Anti-Ku70 Antibody (6Y615) is a Rabbit antibody targeting Ku70. Anti-Ku70 Antibody (6Y615) can be used in FCM,ICC/IF,IHC,IP,WB.
Anti-Ku70 Antibody (6Y615)
Anti-Ku70 Antibody (6Y615)
😃Good
Catalog No. TMAC-02341Alias XRCC6_HUMAN, Xrcc6, XRCC 6, X-ray repair cross-complementing protein 6, X-ray repair complementing defective repair in Chinese hamster cells 6, X ray repair complementing defective repair in Chinese hamster cells 6, TLAA, Thyroid-lupus autoantigen, Thyroid lupus autoantigen p70, Thyroid lupus autoantigen, Thyroid autoantigen 70kD (Ku antigen), Thyroid autoantigen, ML8, Lupus Ku autoantigen protein p70, Kup70, Ku70 DNA binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa, Ku p70, Ku autoantigen, 70kDa, Ku autoantigen p70 subunit, Ku 70, G22P1, DNA repair protein XRCC6, CTCBF, CTC75, CTC box-binding factor 75 kDa subunit, CTC box binding factor 75 kDa subunit, ATP-dependent DNA helicase II 70 kDa subunit, ATP-dependent DNA helicase 2 subunit 1, ATP dependent DNA helicase II 70 kDa subunit, ATP dependent DNA helicase 2 subunit 1, 70 kDa subunit of Ku antigen, 5''-dRP lyase Ku70, 5''-deoxyribose-5-phosphate lyase Ku70
Anti-Ku70 Antibody (6Y615) is a Rabbit antibody targeting Ku70. Anti-Ku70 Antibody (6Y615) can be used in FCM,ICC/IF,IHC,IP,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Ku70 Antibody (6Y615) is a Rabbit antibody targeting Ku70. Anti-Ku70 Antibody (6Y615) can be used in FCM,ICC/IF,IHC,IP,WB. |
| Synonyms | XRCC6_HUMAN, Xrcc6, XRCC 6, X-ray repair cross-complementing protein 6, X-ray repair complementing defective repair in Chinese hamster cells 6, X ray repair complementing defective repair in Chinese hamster cells 6, TLAA, Thyroid-lupus autoantigen, Thyroid lupus autoantigen p70, Thyroid lupus autoantigen, Thyroid autoantigen 70kD (Ku antigen), Thyroid autoantigen, ML8, Lupus Ku autoantigen protein p70, Kup70, Ku70 DNA binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa, Ku p70, Ku autoantigen, 70kDa, Ku autoantigen p70 subunit, Ku 70, G22P1, DNA repair protein XRCC6, CTCBF, CTC75, CTC box-binding factor 75 kDa subunit, CTC box binding factor 75 kDa subunit, ATP-dependent DNA helicase II 70 kDa subunit, ATP-dependent DNA helicase 2 subunit 1, ATP dependent DNA helicase II 70 kDa subunit, ATP dependent DNA helicase 2 subunit 1, 70 kDa subunit of Ku antigen, 5''-dRP lyase Ku70, 5''-deoxyribose-5-phosphate lyase Ku70 |
| Ig Type | IgG |
| Clone | 6Y615 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; ICC/IF: 1:50-200; IP: 1:10-50; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The Ku protein is localized in the nucleus and is composed of subunits referred to as Ku-70 (p70) and Ku-86 (p86) which is also known by the synonym Ku-80 or (p80). Ku was first described as an autoantigen to which antibodies were produced in a patient with scleroderma polymyositis overlap syndrome, and was later found in the sera of patients with other rheumatic diseases. Both subunits of the Ku protein have been cloned, and a number of functions have been proposed for Ku, including cell signaling, DNA replication and transcriptional activation. Ku is involved in Pol II-directed transcription by virtue of its DNA binding activity, serving as the regulatory component of the DNA-associated protein kinase that phosphorylates Pol II and transcription factor Sp. Ku proteins also activate transcription from the U1 small nuclear RNA and the human transferrin receptor gene promoters. A Ku-related protein designated the enhancer 1 binding factor (E1BF), composed of two subunits, has been identified as a positive regulator of RNA polymerase I transcription initiation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 70 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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