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Etifoxine

Name: Etifoxine
Brand: TargetMol
SKU: T13691
Rating: 4.5 (1 reviews)

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Catalog No. T13691Cas No. 21715-46-8

Alias HOE 36-801

Etifoxine preferentially acts on β2 or β3 subunit-containing GABAA receptors. GABAA receptor Etifoxine exhibits anxiolytic activity in rodents and humans with no sedative, myorelaxant or mnesic side effects. Etifoxine acts as a ligand of the translocator protein (TSPO); promotes axonal regeneration. Etifoxine(HOE 36-801) is potentiator of GABAA receptor function in cultured neurons.

Etifoxine

😃Good

Catalog No. T13691Alias HOE 36-801Cas No. 21715-46-8

Pack Size	Price	Availability	Quantity
2 mg	$35	5 days

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Product Introduction

Bioactivity

Description	Etifoxine preferentially acts on β2 or β3 subunit-containing GABAA receptors. GABAA receptor Etifoxine exhibits anxiolytic activity in rodents and humans with no sedative, myorelaxant or mnesic side effects. Etifoxine acts as a ligand of the translocator protein (TSPO); promotes axonal regeneration. Etifoxine(HOE 36-801) is potentiator of GABAA receptor function in cultured neurons.
Synonyms	HOE 36-801

Chemical Properties

Molecular Weight	300.78
Formula	C₁₇H₁₇ClN₂O
Cas No.	21715-46-8
Relative Density.	1.2g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (332.47 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3247 mL	16.6234 mL	33.2469 mL	166.2345 mL
5 mM	0.6649 mL	3.3247 mL	6.6494 mL	33.2469 mL
10 mM	0.3325 mL	1.6623 mL	3.3247 mL	16.6234 mL
20 mM	0.1662 mL	0.8312 mL	1.6623 mL	8.3117 mL
50 mM	0.0665 mL	0.3325 mL	0.6649 mL	3.3247 mL
100 mM	0.0332 mL	0.1662 mL	0.3325 mL	1.6623 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc