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Anti-ISL1 Antibody (8S951) (Synonyms: Islet-1, ISL 1, Insulin gene enhancer protein ISL-1)

Catalog No. TMAC-02245 Copy Product Info
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Anti-ISL1 Antibody (8S951) is a Rabbit antibody targeting ISL1. Anti-ISL1 Antibody (8S951) can be used in ICC/IF,IP,WB.

Anti-ISL1 Antibody (8S951)

Copy Product Info
🥰Excellent
Catalog No. TMAC-02245
Synonyms Islet-1, ISL 1, Insulin gene enhancer protein ISL-1

Anti-ISL1 Antibody (8S951) is a Rabbit antibody targeting ISL1. Anti-ISL1 Antibody (8S951) can be used in ICC/IF,IP,WB.

Anti-ISL1 Antibody
(8S951)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4967-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ISL1 Antibody (8S951) is a Rabbit antibody targeting ISL1. Anti-ISL1 Antibody (8S951) can be used in ICC/IF,IP,WB.
SynonymsIslet-1, ISL 1, Insulin gene enhancer protein ISL-1
Ig Type
IgG
Clone
8S951
Reactivity
Human,Mouse
Verified Activity
1. Western blot analysis of Islet 1 on MCF-7 cell lysates using anti-Islet 1 antibody at 1/1,000 dilution.
2. ICC staining Islet 1 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:1000; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundIslet-1 (ISL1 transcription factor, LIM/homeodomain) and Islet-2 (ISL2 transcription factor, LIM/homeodomain) contain amino-terminal LIM domains and a carboxy-terminal homeodomain and both influence developmental events. Islet-1 influences embryogenesis of the pancreatic islets of Langerhans and neural tube motor neuron differentiation. In developing mouse teeth, Islet-1 mediates patterning of dentition as an activator of Bmp4 expression in incisor (distal) areas of the stomatodeal epithelium. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Islet-2 activity in newly generated motor neurons permits the diversification of visceral and somatic motor neuron subtypes in the developing spinal cord. Murine Islet-2 specifies retinal ganglion cell (RGC) laterality by repressing an ipsilateral pathfinding program unique to the ventral-temporal crescent (VTC) of RGCs in a Zic2- and EphB1-dependent manner.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 39 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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