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Yadanzioside A

🥰Excellent
Catalog No. TN2319Cas No. 95258-15-4
Alias YadanziosideA

Yadanzioside A is a quassinoid and terpenoid extracted from Brucea javanica with antipancreatic cancer activity, inhibition of InhA enzyme (Mycobacterium enoyl acyl carrier protein reductase) and potential as an anti-tuberculosis (TB) drug.

Yadanzioside A

Yadanzioside A

🥰Excellent
Purity: 99.92%
Catalog No. TN2319Alias YadanziosideACas No. 95258-15-4
Yadanzioside A is a quassinoid and terpenoid extracted from Brucea javanica with antipancreatic cancer activity, inhibition of InhA enzyme (Mycobacterium enoyl acyl carrier protein reductase) and potential as an anti-tuberculosis (TB) drug.
Pack SizePriceAvailabilityQuantity
1 mg$269In Stock
5 mg$670In Stock
10 mg$953In Stock
25 mg$1,420In Stock
50 mg$1,920In Stock
1 mL x 10 mM (in DMSO)$1,020In Stock
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Purity:99.92%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
Yadanzioside A is a quassinoid and terpenoid extracted from Brucea javanica with antipancreatic cancer activity, inhibition of InhA enzyme (Mycobacterium enoyl acyl carrier protein reductase) and potential as an anti-tuberculosis (TB) drug.
In vitro
Yadanzioside A exhibits certain antitumor activity, especially against pancreatic cancer cell lines (PANC-1 and SW1990).
SynonymsYadanziosideA
Chemical Properties
Molecular Weight684.68
FormulaC32H44O16
Cas No.95258-15-4
SmilesC(OC)(=O)[C@]12[C@]3([C@]4([C@@]([C@]5(C)[C@@](C[C@]4(OC(=O)[C@@H]3OC(CC(C)C)=O)[H])([C@H](C)C(=O)C(O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)=C5)[H])([C@@H](O)[C@@H]1O)[H])CO2)[H]
Relative Density.1.52 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 40 mg/mL (58.42 mM), Sonication is recommended.
Ethanol: 20 mg/mL (29.21 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (1.46 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM1.4605 mL7.3027 mL14.6054 mL73.0268 mL
5 mM0.2921 mL1.4605 mL2.9211 mL14.6054 mL
10 mM0.1461 mL0.7303 mL1.4605 mL7.3027 mL
20 mM0.0730 mL0.3651 mL0.7303 mL3.6513 mL
DMSO
1mg5mg10mg50mg
50 mM0.0292 mL0.1461 mL0.2921 mL1.4605 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Keywords

Yadanzioside A
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