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Anti-DHX58 Antibody (1Q521)
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Catalog No. TMAC-01146
Alias RNA helicase LGP2, RLR, RIG-I-like receptor LGP2, Protein D11Lgp2 homolog, Probable ATP-dependent RNA helicase DHX58, Probable ATP-dependent helicase LGP2, Probable ATP dependent RNA helicase DHX58, Probable ATP dependent helicase LGP2, Ortholog of mouse D11lgp2, LGP2, LGP 2, DHX58_HUMAN, DHX58, DHX 58, DEXH box polypeptide 58, DEXH (Asp Glu X His) box polypeptide 58, D11lgp2e, D11LGP2
Anti-DHX58 Antibody (1Q521) is a Mouse antibody targeting DHX58. Anti-DHX58 Antibody (1Q521) can be used in WB,FCM.
Anti-DHX58 Antibody (1Q521)
Anti-DHX58 Antibody (1Q521)
😃Good
Catalog No. TMAC-01146Alias RNA helicase LGP2, RLR, RIG-I-like receptor LGP2, Protein D11Lgp2 homolog, Probable ATP-dependent RNA helicase DHX58, Probable ATP-dependent helicase LGP2, Probable ATP dependent RNA helicase DHX58, Probable ATP dependent helicase LGP2, Ortholog of mouse D11lgp2, LGP2, LGP 2, DHX58_HUMAN, DHX58, DHX 58, DEXH box polypeptide 58, DEXH (Asp Glu X His) box polypeptide 58, D11lgp2e, D11LGP2
Anti-DHX58 Antibody (1Q521) is a Mouse antibody targeting DHX58. Anti-DHX58 Antibody (1Q521) can be used in WB,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $426 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-DHX58 Antibody (1Q521) is a Mouse antibody targeting DHX58. Anti-DHX58 Antibody (1Q521) can be used in WB,FCM. |
| Synonyms | RNA helicase LGP2, RLR, RIG-I-like receptor LGP2, Protein D11Lgp2 homolog, Probable ATP-dependent RNA helicase DHX58, Probable ATP-dependent helicase LGP2, Probable ATP dependent RNA helicase DHX58, Probable ATP dependent helicase LGP2, Ortholog of mouse D11lgp2, LGP2, LGP 2, DHX58_HUMAN, DHX58, DHX 58, DEXH box polypeptide 58, DEXH (Asp Glu X His) box polypeptide 58, D11lgp2e, D11LGP2 |
| Clone | 1Q521 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of DHX58 on human DHX58 recombinant protein using anti-DHX58 antibody at 1/1,000 dilution. 2. Western blot analysis of DHX58 on HEK293 (1) and DHX58-hIgGFc transfected HEK293 (2) cell lysate using anti-DHX58 antibody at 1/1,000 dilution. 3. Flow cytometric analysis of Hela cells with DHX58 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Helicases are enzymes that catalyze the separation of double stranded DNA or RNA by utilizing ATP. LGP2, also known as probable ATP-dependent RNA helicase DHX58, is a 678 amino acid protein belonging to the helicase family. LGP2 acts as a negative regulator of host innate immune defense against viruses by binding dsRNA produced during viral replication. The repressor domain of LGP2 binds to RIG-I, a signaling protein involved in host defenses against hepatitis C virus (HCV). By preventing RIG-I multimerization, LGP2 negatively regulates RIG-I-mediated signaling. Localized to the cytoplasm, LGP2 contains one helicase ATP-binding domain and one helicase C-terminal domain. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 77 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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