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Anti-CTLA-4 Antibody (3W218)
😃Good
Catalog No. TMAY-03328
Alias IDDM12, GSE, GRD4, cytotoxic T-lymphocyte-associated protein 4, CTLA-4, CELIAC3, CD152, CD, ALPS5
Anti-CTLA-4 Antibody (3W218) is a Rabbit antibody targeting CTLA-4. Anti-CTLA-4 Antibody (3W218) can be used in ELISA.
Anti-CTLA-4 Antibody (3W218)
Anti-CTLA-4 Antibody (3W218)
😃Good
Catalog No. TMAY-03328Alias IDDM12, GSE, GRD4, cytotoxic T-lymphocyte-associated protein 4, CTLA-4, CELIAC3, CD152, CD, ALPS5
Anti-CTLA-4 Antibody (3W218) is a Rabbit antibody targeting CTLA-4. Anti-CTLA-4 Antibody (3W218) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Mouse |
| Alias | IDDM12, GSE, GRD4, cytotoxic T-lymphocyte-associated protein 4, CTLA-4, CELIAC3, CD152, CD, ALPS5 |
| Ig Type | Rabbit IgG |
| Clone | 3W218 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CTLA-4 / CD152 (rM CTLA-4 / CD152; TMPY-01604; NP_033973.2; Met1-Phe162). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands or counterreceptors for these two proteins are the B7 family members, CD80 (B7-1) and CD86 (B7-2). CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may play an important role in their functions. CD152 or cytotoxic T lymphocyte antigen-4 (CTLA-4) is an essential receptor involved in the negative regulation of T cell activation. Because of its profound inhibitory role, CD152 has been considered a sound susceptible candidate in autoimmunity and a persuasive target for cancer immunotherapy. In particular, recent evidence suggests that CD152 is also important in the homeostasis and function of a population of suppressive cells, termed regulatory T cells (Treg).Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsCTLA4 / CD152 Immune Checkpoint ProteinsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Mouse CTLA-4 / CD152 protein (TMPY-01604) |
| Antigen Species | Mouse |
| Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules, Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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