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Anti-NKX2.2 Antibody (1F181)
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Catalog No. TMAC-02851
Alias tinman, Nkx2b, NKX22_HUMAN, NKX2-2, NKX22, NKX2 2, NK2 transcription factor related locus 2, NK2 transcription factor like protein B, NK2 homeobox 2, NK 2 homolog B, Homeobox protein Nkx-2.2, Homeobox protein Nkx 2.2, Homeobox protein NK-2 homolog B, Homeobox protein NK 2 homolog B
Anti-NKX2.2 Antibody (1F181) is a Mouse antibody targeting NKX2.2. Anti-NKX2.2 Antibody (1F181) can be used in WB,FCM.
Anti-NKX2.2 Antibody (1F181)
Anti-NKX2.2 Antibody (1F181)
😃Good
Catalog No. TMAC-02851Alias tinman, Nkx2b, NKX22_HUMAN, NKX2-2, NKX22, NKX2 2, NK2 transcription factor related locus 2, NK2 transcription factor like protein B, NK2 homeobox 2, NK 2 homolog B, Homeobox protein Nkx-2.2, Homeobox protein Nkx 2.2, Homeobox protein NK-2 homolog B, Homeobox protein NK 2 homolog B
Anti-NKX2.2 Antibody (1F181) is a Mouse antibody targeting NKX2.2. Anti-NKX2.2 Antibody (1F181) can be used in WB,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $427 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-NKX2.2 Antibody (1F181) is a Mouse antibody targeting NKX2.2. Anti-NKX2.2 Antibody (1F181) can be used in WB,FCM. |
| Synonyms | tinman, Nkx2b, NKX22_HUMAN, NKX2-2, NKX22, NKX2 2, NK2 transcription factor related locus 2, NK2 transcription factor like protein B, NK2 homeobox 2, NK 2 homolog B, Homeobox protein Nkx-2.2, Homeobox protein Nkx 2.2, Homeobox protein NK-2 homolog B, Homeobox protein NK 2 homolog B |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of NKX2.2 on human NKX2.2 recombinant protein using anti-NKX2.2 antibody at 1/1,000 dilution. 2. Flow cytometric analysis of MCF-7 cells with NKX2.2 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
| Application | |
| Recommended Dose | WB: 1:500-1000; FCM: 1:100-200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
| Research Background | Members of the NK-2 family of homeodomain proteins are key regulators of growth and development in several tissues, including brain, heart and pancreas. During neural development, sonic hedgehog (Shh) is known to control cell fate and mitogenesis, which is correlated with Shh dose-dependent expression of several genes, including Nkx-2.1, Nkx-2.2 and Nkx-2.9. Specifically, the Nkx-2.2 protein is responsible for directing ventral neuronal patterning in response to graded Shh signaling. In the pancreas, Nkx-2.2 is expressed in a, b and pancreatic polypeptide (PP) cells, but not in d cells. Nkx-2.2 expression is required for differentiation of pancreatic b cells, which produce insulin. Homozygous null mutations of the Nkx-2.2 gene in mice lead to severe hyperglycemia and death shortly after birth, which suggests that Nkx-2.2 may be an important therapeutic target for pancreatic diseases, including diabetes and cancer. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 30 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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