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Anti-Thioredoxin/TRX Antibody (2M628)
😃Good
Catalog No. TMAC-04030
Alias TXN, TRX1, TRX, TRDX, Thioredoxin, Surface-Associated Sulphydryl Protein, SASP, ATL-Derived Factor, ADF
Anti-Thioredoxin/TRX Antibody (2M628) is a Rabbit antibody targeting Thioredoxin/TRX. Anti-Thioredoxin/TRX Antibody (2M628) can be used in FCM,WB.
Anti-Thioredoxin/TRX Antibody (2M628)
Anti-Thioredoxin/TRX Antibody (2M628)
😃Good
Catalog No. TMAC-04030Alias TXN, TRX1, TRX, TRDX, Thioredoxin, Surface-Associated Sulphydryl Protein, SASP, ATL-Derived Factor, ADF
Anti-Thioredoxin/TRX Antibody (2M628) is a Rabbit antibody targeting Thioredoxin/TRX. Anti-Thioredoxin/TRX Antibody (2M628) can be used in FCM,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Thioredoxin/TRX Antibody (2M628) is a Rabbit antibody targeting Thioredoxin/TRX. Anti-Thioredoxin/TRX Antibody (2M628) can be used in FCM,WB. |
| Synonyms | TXN, TRX1, TRX, TRDX, Thioredoxin, Surface-Associated Sulphydryl Protein, SASP, ATL-Derived Factor, ADF |
| Ig Type | IgG |
| Clone | 2M628 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of TRX1 on different lysates using anti-TRX1 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: 293T. 2. Flow cytometric analysis of Hela cells with TRX1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.   |
| Application | |
| Recommended Dose | WB: 1:1000-5000; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Thioredoxin (Trx) is a redox protein that is found in several species, such as bacteria, plants and mammals, and contains a conserved active site, consisting of Trp-Cys-Gly-Pro-Cys. Trx has several biological functions. It acts as a hydrogen donor for ribonucleotide reductase, which is critical for DNA synthesis, and modulates the DNA-binding activity of several transcription factors, including NFkB, AP-1, p53, TFIIIC and glucocorticoid receptor. Trx also stimulates cell growth, is an inhibitor of apoptosis and plays a role in the protection against oxidative stress. Drugs that inhibit Trx have antitumor activity, suggesting that Trx is involved in a variety of human diseases, including cancer. TrxR is a ubiquitously expressed flavoprotein that catalyzes the NADPH-dependent reduction of Trx as well as several other oxidized cellular components. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 12 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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