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Synonyms: WD repeat type I transmembrane protein A72.5, OTTHUMP00000020680, OTTHUMP00000020679, Mitotic checkpoint protein BUB3, Mitotic checkpoint component, Hbub3, C78067, Budding uninhibited by benzimidazoles 3, S. cerevisiae, homolog of, Budding uninhibited by benzimidazoles 3 homolog (yeast), Budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae), Budding uninhibited by benzimidazoles 3 homolog, Budding uninhibited by benzimidazoles 3, budding uninhibited by benomyl, BUB3L, BUB3_HUMAN, BUB3 mitotic checkpoint protein, BUB3 budding uninhibited by benzimidazoles 3 homolog, BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog, bub3, BUB 3L, BUB 3, AW146323, AU043350, AU021329, AU019800, Aa2-050
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
| Description | Anti-BUB3 Antibody (9N253) is a Rabbit antibody targeting BUB3. Anti-BUB3 Antibody (9N253) can be used in FCM,ICC,IF,IHC,IP,WB. |
| Synonyms | WD repeat type I transmembrane protein A72.5, OTTHUMP00000020680, OTTHUMP00000020679, Mitotic checkpoint protein BUB3, Mitotic checkpoint component, Hbub3, C78067, Budding uninhibited by benzimidazoles 3, S. cerevisiae, homolog of, Budding uninhibited by benzimidazoles 3 homolog (yeast), Budding uninhibited by benzimidazoles 3 homolog (S. cerevisiae), Budding uninhibited by benzimidazoles 3 homolog, Budding uninhibited by benzimidazoles 3, budding uninhibited by benomyl, BUB3L, BUB3_HUMAN, BUB3 mitotic checkpoint protein, BUB3 budding uninhibited by benzimidazoles 3 homolog, BUB3 (budding uninhibited by benzimidazoles 3, yeast) homolog, bub3, BUB 3L, BUB 3, AW146323, AU043350, AU021329, AU019800, Aa2-050 |
| Ig Type | IgG |
| Clone | 9N253 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200; IP: 1:10-50; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | BUB3 (budding uninhibited by benzimidazoles 3 homolog), also known as BUB3L or hBUB3, is a conserved component of the mitotic spindle assembly complex (MCC). It contains five WD repeat domains and forms cell cycle constitutive complexes with BUB1 and BUBR1. BUB3 is essential for the kinetochore localization of BUB1 and BUBR1. As a component of the MCC, BUB3 is involved in the essential spindle checkpoint pathway that operates during early embryogenesis. The spindle checkpoint pathway functions to postpone the initiation of anaphase until chromosomes are properly attached to the spindle. This acts to ensure accurate chromosome segregation. In addition, BUB3 plays a role in regulating the establishment of correct kinetochore-microtubule attachments. BUB3 is also thought to bind Tctex1L (or DYNLT3), a dynein light chain. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: N-terminus human Bub3 |
| Antigen Species | Human |
| Uniprot ID |
| Molecular Weight | Theoretical: 37 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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