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Romlusevimab (Synonyms: BRII-198, BRII198)
Catalog No. T77165 Copy Product Info
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Romlusevimab (BRII-198) is a recombinant antibody targeting the spike protein of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), with antiviral activity, used for research on COVID-19 infection.
Romlusevimab
Copy Product Info🥰Excellent
Catalog No. T77165
Synonyms BRII-198, BRII198
Romlusevimab (BRII-198) is a recombinant antibody targeting the spike protein of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), with antiviral activity, used for research on COVID-19 infection.
Romlusevimab
Cas No. 2509447-08-7
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $289 | - | In Stock | |
| 5 mg | $753 | - | In Stock | |
| 10 mg | $1,180 | - | In Stock | |
| 25 mg | $1,780 | - | In Stock | |
| 50 mg | $2,380 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:100% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
Antibody Information
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| Description | Romlusevimab (BRII-198) is a recombinant antibody targeting the spike protein of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), with antiviral activity, used for research on COVID-19 infection. |
| In vitro | Romlusevimab showed a high binding affinity for RBD with an equilibrium dissociation constant (KD) of 0.56 nM. The mixture of Amubarvimab and Romlusevimab blocks the binding of human ACE2 receptor to RBD, IC50 = 16.36 nM. The neutralizing activity of Romlusevimab against Neut99 was 2.50 μg/mL. [1] |
| In vivo | Amubarvimab and Romlusevimab at a 1:1 mixture of 10 mg/kg or 50 mg/kg intritoneally injected into hamsters showed potent activity against SARS-CoV-2. [1] |
| Synonyms | BRII-198, BRII198 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | Spike RBD |
| Molecular Weight | 143.4 kDa |
| Cas No. | 2509447-08-7 |
| Isotype | Human IgG1 lambda C2 |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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