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Anti-BCL10 Antibody (4H852)
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Catalog No. TMAC-00388
Alias Mammalian CARD-containing adapter molecule E10 (mE10), CLAP, CIPER, Cellular-E10 (c-E10), Cellular homolog of vCARMEN (cCARMEN), CED-3/ICH-1 prodomain homologous E10-like regulator (CIPER), CARD-like apoptotic protein (hCLAP), CARD-containing molecule enhancing NF-kappa-B, Bcl10, B-cell lymphoma/leukemia 10, B-cell CLL/lymphoma 10 (Bcl-10)
Anti-BCL10 Antibody (4H852) is a Rabbit antibody targeting BCL10. Anti-BCL10 Antibody (4H852) can be used in ICC/IF,IHC,IP,WB.
Anti-BCL10 Antibody (4H852)
Anti-BCL10 Antibody (4H852)
😃Good
Catalog No. TMAC-00388Alias Mammalian CARD-containing adapter molecule E10 (mE10), CLAP, CIPER, Cellular-E10 (c-E10), Cellular homolog of vCARMEN (cCARMEN), CED-3/ICH-1 prodomain homologous E10-like regulator (CIPER), CARD-like apoptotic protein (hCLAP), CARD-containing molecule enhancing NF-kappa-B, Bcl10, B-cell lymphoma/leukemia 10, B-cell CLL/lymphoma 10 (Bcl-10)
Anti-BCL10 Antibody (4H852) is a Rabbit antibody targeting BCL10. Anti-BCL10 Antibody (4H852) can be used in ICC/IF,IHC,IP,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-BCL10 Antibody (4H852) is a Rabbit antibody targeting BCL10. Anti-BCL10 Antibody (4H852) can be used in ICC/IF,IHC,IP,WB. |
| Synonyms | Mammalian CARD-containing adapter molecule E10 (mE10), CLAP, CIPER, Cellular-E10 (c-E10), Cellular homolog of vCARMEN (cCARMEN), CED-3/ICH-1 prodomain homologous E10-like regulator (CIPER), CARD-like apoptotic protein (hCLAP), CARD-containing molecule enhancing NF-kappa-B, Bcl10, B-cell lymphoma/leukemia 10, B-cell CLL/lymphoma 10 (Bcl-10) |
| Ig Type | IgG |
| Clone | 4H852 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Bcl10, also designated CIPER, c-CARMEN and mE10, was first identified as a gene truncated or mutated in MALT B cell lymphomas and other tumor types. Bcl10 is homologous to the equine herpesvirus-2 E10 gene and, like E10, it contains an N-terminal caspase recruitment domain (CARD). Expression of Bcl10 has been shown to induce NFκB activation in a NIK-dependent pathway, and research indicates that the CARD domain is essential for this activation; although in a separate study, Bcl10 by itself did not induce JNK or NFκB activation. Overexpression of Bcl10 has been shown to induce apoptosis in a manner dependent on CARD-mediated oligomerization. Bcl10 has also been shown to play a role in processing of caspase-9 to its active dimer. Other studies have shown that Bcl10 is not mutated in many human tumors and lymphomas. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 31 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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