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Davunetide acetate

🥰Excellent
Catalog No. T21470L
Alias Davunetide acetate(211439-12-2 Free base)

Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS. Davunetide acetate is a microtubule-stabilizing peptide and inhibits Aβ aggregation and Aβ-induced neurotoxicity. Davunetide acetate possesses neuroprotective, neurotrophic, and cognitive protective properties.

Davunetide acetate
Other Forms of Davunetide acetate:
DavunetideT21470211439-12-2
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Davunetide acetate

🥰Excellent
Purity: 99.78%
Catalog No. T21470LAlias Davunetide acetate(211439-12-2 Free base)
Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS. Davunetide acetate is a microtubule-stabilizing peptide and inhibits Aβ aggregation and Aβ-induced neurotoxicity. Davunetide acetate possesses neuroprotective, neurotrophic, and cognitive protective properties.
Pack SizePriceAvailabilityQuantity
1 mg$29In Stock
2 mg$39In Stock
5 mg$57In Stock
10 mg$95In Stock
25 mg$187In Stock
50 mg$280In Stock
100 mg$397In Stock
200 mg$583In Stock
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Purity:99.78%
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Product Introduction

Bioactivity
Description
Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS. Davunetide acetate is a microtubule-stabilizing peptide and inhibits Aβ aggregation and Aβ-induced neurotoxicity. Davunetide acetate possesses neuroprotective, neurotrophic, and cognitive protective properties.
In vivo
In diabetes male Sprague-Dawley rats, Davunetide acetate (2 μg/kg; Intranasally) improves impaired spatial memory and shows protective effects for central nervous system complications[2].
SynonymsDavunetide acetate(211439-12-2 Free base)
Chemical Properties
Molecular Weight884.97
FormulaC38H64N10O14
SmilesCC[C@@H]([C@H](NC([C@@H](NC([C@@H](NC([C@@H]1CCCN1C([C@@H](NC([C@@H](N)CC(N)=O)=O)C)=O)=O)C(C)C)=O)CO)=O)C(N2CCC[C@H]2C(N[C@H](C(O)=O)CCC(N)=O)=O)=O)C.CC(O)=O
SequenceAsn-Ala-Pro-Val-Ser-Ile-Pro-Gln
Sequence ShortNAPVSIPQ
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

βAmyloidβ AmyloidMicrotubuleAssociatedMicrotubule AssociatedmicrotubuleDavunetide AcetateDavunetide acetateBetaAmyloidBeta AmyloidbAmyloidb Amyloidamyloid-β
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