recombinant

Expression system: HEK293 Cells
Length: 20-340, Extracellular Domain
Activity: Not Tested

M-CSF CSF1 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P07141-1.

Expression system: HEK293 Cells
Length: 1-493, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 23-140, Partial
Activity: Cell Activity

Expression system: CHO Cells
Length: 1-265, Full Length
Activity: Cell Activity

Expression system: HEK293 Cells
Length: 1-196 & 1-335, Full Length
Activity: ELISA、Cells

Expression system: HEK293 Cells
Length: 1-232, Full Length
Activity: Cell Activity

Expression system: E. coli
Length: 1-387, Partial
Activity: Not Tested

Expression system: E. coli
Length: 29-151, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 32-194, Full Length of Mature Protein
Activity: Organoid Coculture

Expression system: HEK293 Cells
Length: 27-191, Full Length of Mature Protein of Isoform VEGF165
Activity: BLI、ELISA

Expression system: HEK293 Cells
Length: 311-426, Full Length of Mature Protein
Activity: Organoid Coculture、Cells

Secreted phosphoprotein 1 (SPP1) expression in TAMs isolated from lung adenocarcinoma tissues and PMA-treated THP-1 cells were measured. Macrophage polarization was identified by flow cytometric analysis. Cell migration and apoptosis were assessed by Transwell migration assays and flow cytometric analysis, respectively. SPP1 is highly expressed in tumor tissues and TAMs isolated from patients with an advanced TNM stage, and also in PMA-treated THP-1 cells.

Expression system: E. coli
Length: 960-1125, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 26-760, partial
Activity: ELISA

M-CSF CSF1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.26 kDa and the accession number is XP_045221641.1.

Expression system: E. coli
Length: 28-99, Partial
Activity: ELISA

Latent TGF beta 1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is A0A499FJK2.

Expression system: E. coli
Length: 30-162, Partial
Activity: Cell Activity

Expression system: E. coli
Length: 118-269, Full Length of Mature Protein
Activity: Cell Activity

KEAP1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 69.7 kDa and the accession number is Q14145.

Signal Transducer and Activator of Transcription 1-Alpha Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer termed IFN-gamma-activated factor (GAF), migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellular responses to interferons. Defects in STAT1 are the cause of STAT1 deficiency complete and familial candidiasis type 7.

IL-21 and IL-21R were highly expressed in the lesional skin and peripheral blood of psoriasis patients. IL-21 promoted CD4 T cells proliferation and Th17 cells differentiation and inhibiting Treg cells differentiation by upregulating RORγt expression and downregulating Foxp3 expression, with increased expression and secretion of IL-17A and IL-22.Microbial translocation and the associated immune activation during HIV-1 infection may lead to high expression levels of the IL-21R activation marker in RM B cells, a feature associated with increased apoptosis and a reduced number of these cells in the circulation.

GPR37 (cathepsin Z) is an orphan receptor that belongs to the G-protein coupled receptor 1 family. G protein-coupled receptors are a large protein family comprised of transmembrane receptors that sense molecules outside the cell and activate inside signal transduction pathways and, ultimately, cellular responses. They only exist in eukaryotes, including yeast, choanoflagellates, and animals. These receptors are bonded and activated by light-sensitive compounds, odors, pheromones, hormones, and neurotransmitters. These ligands vary in size from small molecules to peptides to large proteins. G protein-coupled receptors are involved in many diseases and are also the target of approximately 40% of all modern medicinal drugs. GPR37 is expressed in the brain and spinal cord, and at lower levels in the testis, placenta, and liver, but no detectable expression is observed in any other tissue. GPR37 may have a unique functional role in the central nervous system.