recombinant

Varespladib (LY315920), a specific and effective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor(IC50=7 nM), has been investigated for the treatment and prevention of sickle cell disease, vaso-occlusive crisis, and acute coronary syndrome.

SBC-115337 is a PCSK9 inhibitor.

Recombinant Proteinase K, a serine protease, targets the carboxy-terminal peptide bonds of both aliphatic and aromatic amino acids. It is utilized to digest proteins and eradicate contamination in nucleic acid preparations [1].

Recombinant Humanized Type III Collagen 28.6kDa is a synthesized form of humanized Type III collagen with a molecular weight of 28.6kDa. Known as rhCOLIII, it serves multiple biological functions, such as enhancing skin extracellular matrix regeneration and improving the cellular microenvironment. It inhibits the proliferation, migration, and invasion of breast cancer cells. Type III collagen is involved in cell adhesion, migration, proliferation, and differentiation through interactions with integrins.

Recombinant humanized type III collagen (MW 55900) is a recombinant humanized collagen protein, with a molecular weight of 55900 Da, that offers diverse biological functions, such as enhancing skin extracellular matrix regeneration and improving the cellular microenvironment. This compound inhibits the proliferation, migration, and invasion of breast cancer cells. Type III collagen plays a role in cell adhesion, migration, proliferation, and differentiation through interactions with integrins.

Recombinant Humanized Type XVII Collagen is a transmembrane protein that forms hemidesmosomes. It facilitates interactions between stem cells, surrounding cells, and the extracellular matrix, thereby regulating skin homeostasis, aging, and wound healing. Additionally, Recombinant Humanized Type XVII Collagen has distinct cell adhesion sites and signal transduction capabilities, which can modulate cell migration, proliferation, and differentiation.

Recombinant Humanized Type III Collagen 30-40kDa is an innovative biomaterial with anticancer properties. It can activate discoidin domain receptor 1 (DDR1), thereby inhibiting cancer cell autophagy, proliferation, and migration, while inducing apoptosis.

Recombinant Human Luteinizing Hormone is the reconstituted version of Luteinizing hormone (human). This heterodimeric glycoprotein hormone, produced by the pituitary gland (LH), plays a crucial role in human reproduction.

Recombinant endoglycoceramidase II (rEGCase II) is an endo-β-glucosidase that releases intact glycans from the ceramide portion of sphingolipids. It catalyzes the hydrolysis of the β-glycosidic bond between oligosaccharides and ceramide in various sphingolipids.

Recombinant endoglycoceramidase I assisted by activator II (rEGCase I assisted by Activator II) is a mixture of EGCase I and Activator II. EGCase I is a specific hydrolase ideal for comprehensive analysis of glycolipid compounds (GSLs). Activator II enhances the activity of EGCase without requiring any detergents.

Recombinant endoglycoceramidase I (rEGCase I) is a glycosidase that facilitates the hydrolysis of β-glycosidic bonds between oligosaccharides and ceramides. Additionally, it catalyzes transglycosylation reactions, transferring the sugar moiety of glycosphingolipids to the primary hydroxyl groups of various 1-alkanols.

Recombinant endoglycoceramidase II assisted by activator II is a biocatalyst and a key enzyme in new biocatalysis technology. Enzyme engineering focuses on improving the reaction kinetics, substrate selectivity, and activity under extreme conditions (such as low or high pH). By introducing stimulus-responsive modifications to these enzymes, dynamic control of activity becomes feasible.

Creatine Kinase MB (rCK-MB), Recombinant Human (CK-MB), serves as a biological material or organic compound applicable in life science research.

Collagenase H Recombinant effectively digests and breaks down collagen proteins within the extracellular matrix (ECM), particularly collagen III. It plays a crucial role in the isolation and function of rat islets. Additionally, Collagenase H Recombinant is applicable in tissue engineering and cell culture.

Collagenase G Recombinant is involved in the isolation of islets, initiating the digestion of specific collagens from the N-terminal region, with a particular affinity for Col-V.

Recombinant Trypsin is a serine protease that hydrolyzes proteins at the carboxyl side of lysine or arginine.

Fibronectin is a macromolecular glycoprotein found in blood, connective tissue, and cell surfaces that serves as a biomarker for tissue damage.Fibronectin is recognized by the integrin family of surface receptors.Fibronectin is used in the study of primary open-angle glaucoma.Fibronectin is used in the study of primary open-angle glaucoma.Fibronectin is used in the study of metastatic prostat

GLP-1R Agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R; KB = 26.3 nM for the recombinant human receptor).

Telisotuzumab(ABT-700) is a humanized recombinant antibody targeting the therapeutic hepatocyte growth factor receptor (MET) with high affinity for c-Met.Telisotuzumab has inhibitory effects on c-Met signaling and antitumor activity.

Adalimumab (anti-TNF-alpha) is the first fully human recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.

Alirocumab is a human monoclonal antibody that inhibits PCSK9. It is produced by recombinant DNA technology in Chinese hamster ovary cell suspension culture.

FLAG peptide, an eight-amino-acid sequence (Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys), includes an enterokinase-cleavage site and is utilized for the purification of recombinant proteins.

BSH-IN-1 is a potent, covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs; IC50s: 108 nM for B. longum BSH and 427 nM for B. theta BSH).

CRA-026440 hydrochloride is a potent and broad-spectrum HDAC inhibitor. CRA-026440 hydrochloride exhibits Ki values against recombinant HDAC isoenzymes HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10 are 4 nM, 14 nM, 11 nM, 15 nM, 7 nM, and 20 nM, respectively. CRA-026440 hydrochloride exhibits antitumor and antiangiogenic activities.