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Results for "

recombinant

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    384
    TargetMol | Inhibitors_Agonists
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    38
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    TargetMol | Inhibitors_Agonists
Varespladib
LY315920
T2044172732-68-2
Varespladib (LY315920), a specific and effective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor(IC50=7 nM), has been investigated for the treatment and prevention of sickle cell disease, vaso-occlusive crisis, and acute coronary syndrome.
  • $38
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SBC-115337
T9276423148-46-3
SBC-115337 is a PCSK9 inhibitor.
  • $53
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Recombinant Proteinase K
T76202
Recombinant Proteinase K, a serine protease, targets the carboxy-terminal peptide bonds of both aliphatic and aromatic amino acids. It is utilized to digest proteins and eradicate contamination in nucleic acid preparations [1].
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Recombinant Humanized Type III Collagen 28.6kDa
TRP-00002
Recombinant Humanized Type III Collagen 28.6kDa is a synthesized form of humanized Type III collagen with a molecular weight of 28.6kDa. Known as rhCOLIII, it serves multiple biological functions, such as enhancing skin extracellular matrix regeneration and improving the cellular microenvironment. It inhibits the proliferation, migration, and invasion of breast cancer cells. Type III collagen is involved in cell adhesion, migration, proliferation, and differentiation through interactions with integrins.
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Recombinant humanized type III collagen (MW 55900)
TRP-00130
Recombinant humanized type III collagen (MW 55900) is a recombinant humanized collagen protein, with a molecular weight of 55900 Da, that offers diverse biological functions, such as enhancing skin extracellular matrix regeneration and improving the cellular microenvironment. This compound inhibits the proliferation, migration, and invasion of breast cancer cells. Type III collagen plays a role in cell adhesion, migration, proliferation, and differentiation through interactions with integrins.
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Recombinant Humanized Type XVII Collagen
TRP-00152
Recombinant Humanized Type XVII Collagen is a transmembrane protein that forms hemidesmosomes. It facilitates interactions between stem cells, surrounding cells, and the extracellular matrix, thereby regulating skin homeostasis, aging, and wound healing. Additionally, Recombinant Humanized Type XVII Collagen has distinct cell adhesion sites and signal transduction capabilities, which can modulate cell migration, proliferation, and differentiation.
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Recombinant Humanized Type III Collagen (10.4kDa)
TRP-00174
Recombinant Humanized Type III Collagen 30-40kDa is an innovative biomaterial with anticancer properties. It can activate discoidin domain receptor 1 (DDR1), thereby inhibiting cancer cell autophagy, proliferation, and migration, while inducing apoptosis.
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Fibronectin (recombinant human)
T4096086088-83-7
Fibronectin is a macromolecular glycoprotein found in blood, connective tissue, and cell surfaces that serves as a biomarker for tissue damage.Fibronectin is recognized by the integrin family of surface receptors.Fibronectin is used in the study of primary open-angle glaucoma.Fibronectin is used in the study of primary open-angle glaucoma.Fibronectin is used in the study of metastatic prostat
  • $232
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BAY-524
T145051445830-39-6
BAY-524 is an inhibitor of Bub1(IC50 = 450 nM.human Bub1 in the presence of 2 mM ATP).
  • $93
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GLP-1R Agonist DMB
T36579281209-71-0
GLP-1R Agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R; KB = 26.3 nM for the recombinant human receptor).
  • $47
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Telisotuzumab
Mab-224G11, ABT-700
T774371781223-80-0
Telisotuzumab(ABT-700) is a humanized recombinant antibody targeting the therapeutic hepatocyte growth factor receptor (MET) with high affinity for c-Met.Telisotuzumab has inhibitory effects on c-Met signaling and antitumor activity.
  • $372
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Adalimumab
T9901331731-18-1
Adalimumab (anti-TNF-alpha) is the first fully human recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.
  • $213
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Alirocumab
T99161245916-14-6
Alirocumab is a human monoclonal antibody that inhibits PCSK9. It is produced by recombinant DNA technology in Chinese hamster ovary cell suspension culture.
  • $372
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FLAG peptide
TP127398849-88-8
FLAG peptide, an eight-amino-acid sequence (Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys), includes an enterokinase-cleavage site and is utilized for the purification of recombinant proteins.
  • $30
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BSH-IN-1
T106232553217-91-5In house
BSH-IN-1 is a potent, covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs; IC50s: 108 nM for B. longum BSH and 427 nM for B. theta BSH).
  • $118
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CRA-026440 hydrochloride
CRA-026440 hydrochloride(847460-34-8 Free base)
T10883L847459-98-7In house
CRA-026440 hydrochloride is a potent and broad-spectrum HDAC inhibitor. CRA-026440 hydrochloride exhibits Ki values against recombinant HDAC isoenzymes HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10 are 4 nM, 14 nM, 11 nM, 15 nM, 7 nM, and 20 nM, respectively. CRA-026440 hydrochloride exhibits antitumor and antiangiogenic activities.
  • $117
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hDHODH-IN-4
DHODH-IN-5
T110281644156-56-8In house
hDHODH-IN-4 (DHODH-IN-5) is a potent inhibitor of human dihydrogen dehydrogenase (DHODH). For human recombinant DHODH, its pIC50 is 7.8. hDHODH-IN-4 inhibits measles virus replication with a pMIC50 of 8.8.
  • $68
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DMCM hydrochloride
T110611215833-62-7In house
DMCM hydrochloride is a non-selective fully inverse agonist of benzodiazepine. DMCM showed significant differences in human recombinant GABAA αxβ3γ2 receptor subtypes. For α1, α2, α3, and α5 receptors, their Kis were 10 nM, 13 nM, 7.5 nM, 2.2 nM, respectively.
  • $31
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Lp-PLA2-IN-3
T118742196245-16-4In house
Lp-PLA2-IN-3 is a potent, orally bioactive lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, effectively inhibiting recombinant human [Lp-PLA2] with an IC50 value of 14 nM.
  • $97
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Bamirastine
TAK-427
T13566215529-47-8In house
Bamirastine inhibits ligand binding to recombinant human histamine H1 receptor (rhH1R) with an IC50 of 17.3 nM and possesses an inhibitory effect on allergic skin inflammation.
  • $700
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CCT367766
T149082229856-58-8In house
CCT367766 is a potent, PROTAC-based, third-generation, iso-functional pirin-targeted protein degradation probe (PDP) that depletes pirin expression at low concentrations.CCT367766 has an IC50 value of 490 nM for the CRBN-DDB1 complex.CCT367766 has a good affinity for recombinant pirin and CRBN. CCT367766 has a good affinity for recombinant pirin and CRBN, with Kd values of 55 nM and 120 nM, respectively. cct367766 is a potent orally active protein that reduces the expression of pirin at low concentrations.
  • $293
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Ranirestat
SX-3030, SX3030, AS-3201, AS3201, AS 3201
T16723147254-64-6In house
Ranirestat (AS-3201) is an orally active and potent aldose reductase (AR) inhibitor with neuroprotective properties that ameliorates peripheral nerve dysfunction in rats with advanced diabetic polyneuropathy.Ranirestat inhibits the inflammatory response of high glucose-exposed endothelial cells and may be useful for the study of diabetic sensory-motor polyneuropathy.
  • $72
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anatibant 2hcl
Anatibant 2HCl(209733-45-9 Free base)
T26627L209788-45-4In house
Anatibant 2HCl is a small molecule bradykinin B2 receptor antagonist for the treatment of neurological disorders and may be used in the study of brain injury.
  • $350
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JTK-109
JTK109
T27696480462-62-2In house
JTK-109 is an inhibitor of hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor and inhibits G1b and G3a subgenomic replicons and recombinant enzymes.
  • $329
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