VNN1 Protein, Mouse, Recombinant (aa 24-488, His)

Catalog No. TMPY-02529U

VNN1 Protein, Mouse, Recombinant (aa 24-488, His) is expressed in HEK293 Cells. The accession number is Q9Z0K8.

VNN1 Protein, Mouse, Recombinant (aa 24-488, His)

Catalog No. TMPY-02529U

VNN1 Protein, Mouse, Recombinant (aa 24-488, His) is expressed in HEK293 Cells. The accession number is Q9Z0K8.

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Product Information

Biological Activity	Activity has not been tested. It is theoretically active, but we cannot guarantee it.
Description	VNN1 Protein, Mouse, Recombinant (aa 24-488, His) is expressed in HEK293 Cells. The accession number is Q9Z0K8.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-His
Accession Number	Q9Z0K8
Synonyms	vanin 1,V-1
Construction	Leu24-Asn488
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	53.14 kDa (Predicted); 55-70 kDa (Due to glycosylation)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	Vanin-1 (VNN1) is anchored to the cellular membrane with pantetheinase activity, which hydrolyzes pantetheine to produce cysteamine. VNN1 can promote oxidative stress and the inflammatory response. Additionally, VNN1 has been confirmed to be overexpressed in cancer tissues of patients with PCAD and can be used as a blood biomarker for the discrimination of PCAD from type 2 diabetes.