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Anti-CTNNB1 Antibody (8Y337) (Synonyms: PRO2286, OK/SW-cl.35, NEDSDV, MRD19, EVR7, CTNNB, beta-catenin, a...)

Catalog No. TMAC-00429 Copy Product Info
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Anti-CTNNB1 Antibody (8Y337) is a Rabbit antibody targeting CTNNB1. Anti-CTNNB1 Antibody (8Y337) can be used in ICC,IHC,IP,WB.

Anti-CTNNB1 Antibody (8Y337)

Copy Product Info
🥰Excellent
Catalog No. TMAC-00429
Synonyms PRO2286, OK/SW-cl.35, NEDSDV, MRD19, EVR7, CTNNB, beta-catenin, armadillo

Anti-CTNNB1 Antibody (8Y337) is a Rabbit antibody targeting CTNNB1. Anti-CTNNB1 Antibody (8Y337) can be used in ICC,IHC,IP,WB.

Anti-CTNNB1 Antibody
(8Y337)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CTNNB1 Antibody (8Y337) is a Rabbit antibody targeting CTNNB1. Anti-CTNNB1 Antibody (8Y337) can be used in ICC,IHC,IP,WB.
SynonymsPRO2286, OK/SW-cl.35, NEDSDV, MRD19, EVR7, CTNNB, beta-catenin, armadillo
Ig Type
IgG
Clone
8Y337
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-5000; IHC: 1:20-200; ICC: 1:20-50; IP: 1:10-50
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research Backgroundβ-Catenin is a key downstream effector in the Wnt signaling pathway. It is implicated in two major biological processes in vertebrates: early embryonic development and tumorigenesis. Phosphorylation at Ser-552 by AMPK promotes stabilizion of the protein, enhancing TCF/LEF-mediated transcription. Phosphorylation on Tyr-654 decreases CDH1 binding and enhances TBP binding. GSK-3β destabilizes β-catenin by phosphorylating it at Ser33, Ser37, and Thr41. Mutations at these sites result in the stabilization of β-catenin protein levels and have been found in many tumor cell lines.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 92 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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