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Anti-CTNNB1 Antibody (8Y337)

😃Good
Catalog No. TMAC-00429

Anti-CTNNB1 Antibody (8Y337) is a Rabbit antibody targeting CTNNB1. Anti-CTNNB1 Antibody (8Y337) can be used in WB,ICC,IHC,IP.

Anti-CTNNB1 Antibody (8Y337)

Anti-CTNNB1 Antibody (8Y337)

😃Good
Catalog No. TMAC-00429
Anti-CTNNB1 Antibody (8Y337) is a Rabbit antibody targeting CTNNB1. Anti-CTNNB1 Antibody (8Y337) can be used in WB,ICC,IHC,IP.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-CTNNB1 Antibody (8Y337) is a Rabbit antibody targeting CTNNB1. Anti-CTNNB1 Antibody (8Y337) can be used in WB,ICC,IHC,IP.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-5000; IHC: 1:20-200; ICC: 1:20-50; IP: 1:10-50
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research Backgroundβ-Catenin is a key downstream effector in the Wnt signaling pathway. It is implicated in two major biological processes in vertebrates: early embryonic development and tumorigenesis. Phosphorylation at Ser-552 by AMPK promotes stabilizion of the protein, enhancing TCF/LEF-mediated transcription. Phosphorylation on Tyr-654 decreases CDH1 binding and enhances TBP binding. GSK-3β destabilizes β-catenin by phosphorylating it at Ser33, Ser37, and Thr41. Mutations at these sites result in the stabilization of β-catenin protein levels and have been found in many tumor cell lines.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 92 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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