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Anti-CTNNB1 Antibody (8Y337)
😃Good
Catalog No. TMAC-00429
Alias PRO2286, OK/SW-cl.35, NEDSDV, MRD19, EVR7, CTNNB, beta-catenin, armadillo
Anti-CTNNB1 Antibody (8Y337) is a Rabbit antibody targeting CTNNB1. Anti-CTNNB1 Antibody (8Y337) can be used in ICC,IHC,IP,WB.
Anti-CTNNB1 Antibody (8Y337)
Anti-CTNNB1 Antibody (8Y337)
😃Good
Catalog No. TMAC-00429Alias PRO2286, OK/SW-cl.35, NEDSDV, MRD19, EVR7, CTNNB, beta-catenin, armadillo
Anti-CTNNB1 Antibody (8Y337) is a Rabbit antibody targeting CTNNB1. Anti-CTNNB1 Antibody (8Y337) can be used in ICC,IHC,IP,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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Chemical Properties
| Description | Anti-CTNNB1 Antibody (8Y337) is a Rabbit antibody targeting CTNNB1. Anti-CTNNB1 Antibody (8Y337) can be used in ICC,IHC,IP,WB. |
| Synonyms | PRO2286, OK/SW-cl.35, NEDSDV, MRD19, EVR7, CTNNB, beta-catenin, armadillo |
| Ig Type | IgG |
| Clone | 8Y337 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-5000; IHC: 1:20-200; ICC: 1:20-50; IP: 1:10-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | β-Catenin is a key downstream effector in the Wnt signaling pathway. It is implicated in two major biological processes in vertebrates: early embryonic development and tumorigenesis. Phosphorylation at Ser-552 by AMPK promotes stabilizion of the protein, enhancing TCF/LEF-mediated transcription. Phosphorylation on Tyr-654 decreases CDH1 binding and enhances TBP binding. GSK-3β destabilizes β-catenin by phosphorylating it at Ser33, Ser37, and Thr41. Mutations at these sites result in the stabilization of β-catenin protein levels and have been found in many tumor cell lines. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 92 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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