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IL-17A & IL-17F Heterodimer Protein, Mouse, Recombinant (Strep-II & His)

(Synonyms: ML-1, Interleukin-17F, Interleukin-17A, IL24, IL-17F, IL-17A, IL-17, CTLA-8) Copy Product Info

Synonyms: ML-1, Interleukin-17F, Interleukin-17A, IL24, IL-17F, IL-17A, IL-17, CTLA-8

Catalog No. TMPK-01713 Copy Product Info
IL-17A & IL-17F Heterodimer Protein, Mouse, Recombinant (Strep-II & His) is expressed in HEK293 Cells. The accession number is Q62386(IL-17A)&Q7TNI7-1(IL-17F).
IL-17A & IL-17F Heterodimer Protein, Mouse, Recombinant (Strep-II & His)
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Pack SizePriceUSA StockGlobal StockQuantity
5 µg$747-10 days7-10 days
10 µg$1137-10 days7-10 days
20 µg$1757-10 days7-10 days
50 µg$3167-10 days7-10 days
100 µg$4907-10 days7-10 days
200 µg$7937-10 days7-10 days
500 µg$1,4707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized Mouse IL-17A&F, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Mouse IL-17R alpha, hFc Tag with the EC50 of 6.9 ng/ml determined by ELISA (QC Test).
Description
IL-17A & IL-17F Heterodimer Protein, Mouse, Recombinant (Strep-II & His) is expressed in HEK293 Cells. The accession number is Q62386(IL-17A)&Q7TNI7-1(IL-17F).
Species
Mouse
Expression System
HEK293 Cells
TagN-Strep-II, N-His
Accession NumberQ62386(IL-17A)&Q7TNI7-1(IL-17F)
ConstructionAla26-Ala158 (IL-17A) and Arg29-Ala161 (IL-17F)
Protein Purity
> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Endotoxin< 0.1 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsML-1, Interleukin-17F, Interleukin-17A, IL24, IL-17F, IL-17A, IL-17, CTLA-8
Research Background
Interleukin‑17A (IL‑17A), also known as CTLA‑8, is a 15‑20 kDa glycosylated cytokine that plays an important role in anti‑microbial and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold.IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.
Chemical Properties
Molecular Weight16.01 kDa (IL-17A) and 15.98 kDa (IL-17F) (Predicted); 13-23 kDa and 25-35 kDa (Reducing condition, due to glycosylation)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: IL-17A & IL-17F Heterodimer Protein, Mouse, Recombinant (Strep-II & His) chemical structure | IL-17A & IL-17F Heterodimer Protein, Mouse, Recombinant (Strep-II & His) molecular weight