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Anti-Stromal interaction molecule 1 Antibody (8X722)
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Catalog No. TMAB-13248
Anti-Stromal interaction molecule 1 Antibody (8X722) is a Rabbit antibody targeting Stromal interaction molecule 1. Anti-Stromal interaction molecule 1 Antibody (8X722) can be used in FCM, IF, IHC-Fr, IHC-P, IP, WB.
Anti-Stromal interaction molecule 1 Antibody (8X722)
Anti-Stromal interaction molecule 1 Antibody (8X722)
😃Good
Catalog No. TMAB-13248
Anti-Stromal interaction molecule 1 Antibody (8X722) is a Rabbit antibody targeting Stromal interaction molecule 1. Anti-Stromal interaction molecule 1 Antibody (8X722) can be used in FCM, IF, IHC-Fr, IHC-P, IP, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Stromal interaction molecule 1 Antibody (8X722) is a Rabbit antibody targeting Stromal interaction molecule 1. Anti-Stromal interaction molecule 1 Antibody (8X722) can be used in FCM, IF, IHC-Fr, IHC-P, IP, WB. |
| Ig Type | IgG |
| Clone | 8X722 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | FCM=1:50-100; IF=1:50-200; IHC-Fr=1:50-200; IHC-P=1:50-200; IP=1:20-50; WB=1:1000-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. Endoplasmic reticulum membrane. Cytoplasm > cytoskeleton. Translocates from the endoplasmic reticulum to the cell membrane in response to a depletion of intracellular calcium. Associated with the microtubule network at the growing distal tip of microtubules. Tissue Specificity : Ubiquitously expressed in various human primary cells and tumor cell lines. |
| Tissue Specificity | Ubiquitously expressed in various human primary cells and tumor cell lines. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | STIM1 is a potential tumor suppressor; defects in STIM1 may cause rhabdomyosarcoma and rhabdoid tumors. STIM1 can either homodimerize or form heterodimers with STIM2. STIM2 possesses a high sequence identity to STIM1 and can function as an inhibitor of STIM1-mediated plasma membrane store-operated Ca2+ entry. However, further investigation is required to elucidate the true physiological function of STIM2. |
| Immunogen | A synthesized peptide: human Stromal interaction molecule 1 |
| Antigen Species | Human |
| Gene Name | STIM1 |
| Gene ID | |
| Protein Name | Stromal interaction molecule 1 |
| Uniprot ID | |
| Function | Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, TMEM142A/ORAI1. |
| Molecular Weight | Theoretical: 77 kDa. Actual: 77 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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