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Anti-PAI1 Antibody (8G921)
😃Good
Catalog No. TMAB-09935
Anti-PAI1 Antibody (8G921) is a Rabbit antibody targeting PAI1. Anti-PAI1 Antibody (8G921) can be used in FCM, WB.
Anti-PAI1 Antibody (8G921)
Anti-PAI1 Antibody (8G921)
😃Good
Catalog No. TMAB-09935
Anti-PAI1 Antibody (8G921) is a Rabbit antibody targeting PAI1. Anti-PAI1 Antibody (8G921) can be used in FCM, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PAI1 Antibody (8G921) is a Rabbit antibody targeting PAI1. Anti-PAI1 Antibody (8G921) can be used in FCM, WB. |
| Ig Type | IgG |
| Clone | 8G921 |
| Reactivity | Human |
| Application | |
| Recommended Dose | FCM=1:50-100; WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Tissue Specificity | Found in plasma and platelets and in endothelial, hepatoma and fibrosarcoma cells |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 50mM Tris-Glycine (pH7.4), 0.15M NaCl, 40% Glycerol, 0.02% Proclin300 and 0.05% BSA. |
| Concentration | 1mg/ml |
| Research Background | PAI1 (plasminogen activator inhibitor 1) is originally cloned from human endothelial cell (Pannekoek 1986, Ginsburg 1986) and rat hepatoma cell 3 cDNA libraries. As a member of the serpin family of serine protease inhibitors, PAI1 inhibits both tissue type plasminogen activator (tPA) and urokinase type plasminogen activator (uPA). High PAI1 levels are associated with an increased risk of thromboembolic disease while PAI1 deficiency may represent an inherited autosomal recessive bleeding disorder. |
| Immunogen | A synthesized peptide: human PAI 1 |
| Antigen Species | Human |
| Gene Name | SERPINE1 |
| Gene ID | |
| Protein Name | Plasminogen activator inhibitor 1 |
| Uniprot ID | |
| Function | Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis. |
| Molecular Weight | Theoretical: 43 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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