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Anti-GABRA5 Antibody (3J289)

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Catalog No. TMAC-01589
Alias Gamma-aminobutyric acid receptor subunit alpha-5, GABRA 5, GABA(A) receptor subunit alpha-5

Anti-GABRA5 Antibody (3J289) is a Rabbit antibody targeting GABRA5. Anti-GABRA5 Antibody (3J289) can be used in WB,ICC/IF.

Anti-GABRA5 Antibody (3J289)

Anti-GABRA5 Antibody (3J289)

😃Good
Catalog No. TMAC-01589Alias Gamma-aminobutyric acid receptor subunit alpha-5, GABRA 5, GABA(A) receptor subunit alpha-5
Anti-GABRA5 Antibody (3J289) is a Rabbit antibody targeting GABRA5. Anti-GABRA5 Antibody (3J289) can be used in WB,ICC/IF.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-GABRA5 Antibody (3J289) is a Rabbit antibody targeting GABRA5. Anti-GABRA5 Antibody (3J289) can be used in WB,ICC/IF.
SynonymsGamma-aminobutyric acid receptor subunit alpha-5, GABRA 5, GABA(A) receptor subunit alpha-5
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. ICC staining GABA A Receptor alpha 5 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
2. ICC staining GABA A Receptor alpha 5 in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining GABA A Receptor alpha 5 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. Western blot analysis of GABA A Receptor alpha 5 expression in 293T cell lysate.
Application
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundGAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA Rα1-6, GABAA R β1-3, GABAA Rγ1-3, GABAA Rδ, GABAA Rε, GABAA R??1 and GABAA R??2. The GABAB family is composed of GABAB R1α and GABAB R1β. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 70 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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