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Anti-ATF3 Antibody (8F492)

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Catalog No. TMAB-02899 Copy Product Info
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Anti-ATF3 Antibody (8F492) is a Rabbit antibody targeting ATF3. Anti-ATF3 Antibody (8F492) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-ATF3 Antibody
(8F492)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1517-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4727-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ATF3 Antibody (8F492) is a Rabbit antibody targeting ATF3. Anti-ATF3 Antibody (8F492) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
8F492
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1:500-1000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes. [provided by RefSeq, Apr 2011].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human ATF
Antigen Species
Human
Gene Name
ATF3
Gene ID
Protein Name
Cyclic AMP-dependent transcription factor ATF-3
Uniprot ID
Function
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
Chemical Properties
Molecular WeightTheoretical: 20 kDa. Actual: 23 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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