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Anti-HTRA1 Antibody (4Z151)

Catalog No. TMAB-07376 Copy Product Info
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Anti-HTRA1 Antibody (4Z151) is a Rabbit antibody targeting HTRA1. Anti-HTRA1 Antibody (4Z151) can be used in WB,ICC/IF.

Anti-HTRA1 Antibody (4Z151)

Copy Product Info
🥰Excellent
Catalog No. TMAB-07376

Anti-HTRA1 Antibody (4Z151) is a Rabbit antibody targeting HTRA1. Anti-HTRA1 Antibody (4Z151) can be used in WB,ICC/IF.

Anti-HTRA1 Antibody
(4Z151)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1517-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4737-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-HTRA1 Antibody (4Z151) is a Rabbit antibody targeting HTRA1. Anti-HTRA1 Antibody (4Z151) can be used in WB,ICC/IF.
Ig Type
IgG
Clone
4Z151
Reactivity
Human
Verified Activity
Western blot analysis of MCF7 cell lysate. Using HTRA1 (TMAB-07376) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:1000-2000; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted.
Tissue SpecificityExpressed in a variety of tissues, with strongest expression in placenta.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundSerine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space.
Antigen Details
Immunogen
A synthesized peptide: human Serine protease HTRA1
Antigen Species
Human
Gene Name
HTRA1
Gene ID
Protein Name
Serine protease HTRA1
Uniprot ID
Function
Protease that regulate the availability of nsulin-like growth factors (IGFs) by cleaving IGF-binding proteins. Represses signaling by TGF-beta family members.
Chemical Properties
Molecular WeightTheoretical: 51 kDa. Actual: 51 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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