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Anti-HTRA1 Antibody (4Z151)
😃Good
Catalog No. TMAB-07376
Anti-HTRA1 Antibody (4Z151) is a Rabbit antibody targeting HTRA1. Anti-HTRA1 Antibody (4Z151) can be used in WB,ICC/IF.
Anti-HTRA1 Antibody (4Z151)
Anti-HTRA1 Antibody (4Z151)
😃Good
Catalog No. TMAB-07376
Anti-HTRA1 Antibody (4Z151) is a Rabbit antibody targeting HTRA1. Anti-HTRA1 Antibody (4Z151) can be used in WB,ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-HTRA1 Antibody (4Z151) is a Rabbit antibody targeting HTRA1. Anti-HTRA1 Antibody (4Z151) can be used in WB,ICC/IF. |
| Ig Type | IgG |
| Clone | 4Z151 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:1000-2000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Expressed in a variety of tissues, with strongest expression in placenta. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. |
| Immunogen | A synthesized peptide: human Serine protease HTRA1 |
| Antigen Species | Human |
| Gene Name | HTRA1 |
| Gene ID | |
| Protein Name | Serine protease HTRA1 |
| Uniprot ID | |
| Function | Protease that regulate the availability of nsulin-like growth factors (IGFs) by cleaving IGF-binding proteins. Represses signaling by TGF-beta family members. |
| Molecular Weight | Theoretical: 51 kDa. Actual: 51 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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