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Anti-HTRA2 Antibody (2I343)
Catalog No. TMAB-07380 Copy Product Info
🥰Excellent
Anti-HTRA2 Antibody (2I343) is a Rabbit antibody targeting HTRA2. Anti-HTRA2 Antibody (2I343) can be used in WB,IHC-P,IHC-Fr,IP,IF.
Anti-HTRA2 Antibody (2I343)
Copy Product Info🥰Excellent
Catalog No. TMAB-07380
Anti-HTRA2 Antibody (2I343) is a Rabbit antibody targeting HTRA2. Anti-HTRA2 Antibody (2I343) can be used in WB,IHC-P,IHC-Fr,IP,IF.
Anti-HTRA2 Antibody
(2I343)
(2I343)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-HTRA2 Antibody (2I343) is a Rabbit antibody targeting HTRA2. Anti-HTRA2 Antibody (2I343) can be used in WB,IHC-P,IHC-Fr,IP,IF. |
| Ig Type | IgG |
| Clone | 2I343 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 25 ug total protein per lane of various lysates (see on figure) probed with HTRA2 monoclonal antibody, unconjugated (TMAB-07380) at 1: 1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IP: 1:20-50; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion intermembrane space. Mitochondrion membrane; Single-pass membrane protein (Potential). Note=Predominantly present in the intermembrane space. Released into the cytosol following apoptotic stimuli, such as UV treatment, and stimulation of mitochondria with caspase-8 truncated BID/tBID. |
| Tissue Specificity | Isoform 1 is ubiquitous. Isoform 2 is expressed predominantly in the kidney, colon and thyroid. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive. |
| Immunogen | A synthesized peptide: human HTRA2 |
| Antigen Species | Human |
| Gene Name | HTRA2 |
| Gene ID | |
| Protein Name | Serine protease HTRA2, mitochondrial |
| Uniprot ID | |
| Function | Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive. |
| Molecular Weight | Theoretical: 49 kDa. Actual: 38 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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