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Anti-Rack1 Antibody (8C519)

(Synonyms: RACK1, PIG21, HLC-7, H12.3, Gnb2-rs1) Copy Product Info
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Synonyms: RACK1, PIG21, HLC-7, H12.3, Gnb2-rs1

Catalog No. TMAC-03499 Copy Product Info
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Anti-Rack1 Antibody (8C519) is a Rabbit antibody targeting Rack1. Anti-Rack1 Antibody (8C519) can be used in FCM,IHC,WB.
Anti-Rack1 Antibody
(8C519)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Rack1 Antibody (8C519) is a Rabbit antibody targeting Rack1. Anti-Rack1 Antibody (8C519) can be used in FCM,IHC,WB.
SynonymsRACK1, PIG21, HLC-7, H12.3, Gnb2-rs1
Ig Type
IgG
Clone
8C519
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-2000; IHC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundMembers of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. Receptor for activated C kinases, termed RACKs, are intracellular receptors for activated PKC that may be involved in the activation-induced translocation of PKC. RACK1 (receptor for activated C kinase 1) is a 317 amino acid G protein b subunit-like protein that functions as a RACK and inhibits the activity of Src tyrosine kinases. In response to PKC activation, the intracellular localization of RACK1 and PKC bII changes, and RACK1 and PKC bII co-localize to the same sites. RACK1 is therefore thought to be a shuttling protein for PKC bII. A deficit in RACK1 may be associated with impaired PKC activation in the aging brain. The RACK1 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, A.thaliana, rice and P.falciparum, and maps to human chromosome 5q35.3.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: C-terminal human RACK1
Antigen Species
Human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 35 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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