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Anti-GluR1 Antibody (7G200)
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Catalog No. TMAB-06543
Anti-GluR1 Antibody (7G200) is a Rabbit antibody targeting GluR1. Anti-GluR1 Antibody (7G200) can be used in IF, IHC-Fr, IHC-P, IP, WB.
Anti-GluR1 Antibody (7G200)
Anti-GluR1 Antibody (7G200)
😃Good
Catalog No. TMAB-06543
Anti-GluR1 Antibody (7G200) is a Rabbit antibody targeting GluR1. Anti-GluR1 Antibody (7G200) can be used in IF, IHC-Fr, IHC-P, IP, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-GluR1 Antibody (7G200) is a Rabbit antibody targeting GluR1. Anti-GluR1 Antibody (7G200) can be used in IF, IHC-Fr, IHC-P, IP, WB. |
| Ig Type | IgG |
| Clone | 7G200 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; IP=1:20-50; WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell projection, dendrit. Cell projection, dendritic spine. Note=Interaction with CACNG2, CNIH2 and CNIH3 promotes cell surface expression. |
| Tissue Specificity | Widely expressed in brain. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | AMPA- (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), kainate-, and NMDA- (N-methyl-D-aspartate) receptors are the three main families of ionotropic glutamate-gated ion channels. AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4), which assemble as homo- or hetero-tetramers to mediate the majority of fast excitatory transmissions in the central nervous system. AMPARs are implicated in synapse formation, stabilization, and plasticity. |
| Immunogen | A synthesized peptide: human GluR1 |
| Antigen Species | Human |
| Gene Name | GRIA1 |
| Gene ID | |
| Protein Name | Glutamate receptor 1 |
| Uniprot ID | |
| Function | Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. |
| Molecular Weight | Theoretical: 102 kDa. Actual: 102 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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