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Anti-MALT1 Antibody (4D932)
😃Good
Catalog No. TMAB-08537
Anti-MALT1 Antibody (4D932) is a Rabbit antibody targeting MALT1. Anti-MALT1 Antibody (4D932) can be used in WB,ICC/IF,FCM.
Anti-MALT1 Antibody (4D932)
Anti-MALT1 Antibody (4D932)
😃Good
Catalog No. TMAB-08537
Anti-MALT1 Antibody (4D932) is a Rabbit antibody targeting MALT1. Anti-MALT1 Antibody (4D932) can be used in WB,ICC/IF,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-MALT1 Antibody (4D932) is a Rabbit antibody targeting MALT1. Anti-MALT1 Antibody (4D932) can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG |
| Clone | 4D932 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:1000-2000; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm, perinuclear region. Nucleus. Note=Shuttles between the nucleus and cytoplasm. Found in perinuclear structures together with BCL10. |
| Tissue Specificity | Highly expressed in peripheral blood mononuclear cells. Detected at lower levels in bone marrow, thymus and lymph node, and at very low levels in colon and lung. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Protease that enhances BCL10-induced activation: acts via formation of CBM complexes that channel adaptive and innate immune signaling downstream of CARD domain-containing proteins (CARD9, CARD11 and CARD14) to activate NF-kappa-B and MAP kinase p38 pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines. |
| Immunogen | A synthesized peptide: human MALT1 |
| Antigen Species | Human |
| Gene Name | MALT1 |
| Gene ID | |
| Protein Name | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 |
| Uniprot ID | |
| Function | Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion. |
| Molecular Weight | Theoretical: 92 kDa. Actual: 92 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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