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Anti-Glypican 3 Antibody (8G714)
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Catalog No. TMAB-06583
Anti-Glypican 3 Antibody (8G714) is a Rabbit antibody targeting Glypican 3. Anti-Glypican 3 Antibody (8G714) can be used in WB,FCM.
Anti-Glypican 3 Antibody (8G714)
Anti-Glypican 3 Antibody (8G714)
😃Good
Catalog No. TMAB-06583
Anti-Glypican 3 Antibody (8G714) is a Rabbit antibody targeting Glypican 3. Anti-Glypican 3 Antibody (8G714) can be used in WB,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Glypican 3 Antibody (8G714) is a Rabbit antibody targeting Glypican 3. Anti-Glypican 3 Antibody (8G714) can be used in WB,FCM. |
| Ig Type | IgG |
| Clone | 8G714 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 1:20-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane and Secreted, extracellular space. |
| Tissue Specificity | Highly expressed in lung, liver and kidney. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] |
| Immunogen | A synthesized peptide: human Glypican 3 |
| Antigen Species | Human |
| Gene Name | GPC3 |
| Gene ID | |
| Protein Name | Glypican-3 |
| Uniprot ID | |
| Function | Cell surface proteoglycan that bears heparan sulfate. Inhibits the dipeptidyl peptidase activity of DPP4. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition. |
| Molecular Weight | Theoretical: 65 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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