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Anti-Human IgM Antibody (7U224)

😃Good
Catalog No. TMAC-02072

Anti-Human IgM Antibody (7U224) is a Rabbit antibody targeting Human IgM. Anti-Human IgM Antibody (7U224) can be used in WB,IHC,IP.

Anti-Human IgM Antibody (7U224)

Anti-Human IgM Antibody (7U224)

😃Good
Catalog No. TMAC-02072
Anti-Human IgM Antibody (7U224) is a Rabbit antibody targeting Human IgM. Anti-Human IgM Antibody (7U224) can be used in WB,IHC,IP.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-Human IgM Antibody (7U224) is a Rabbit antibody targeting Human IgM. Anti-Human IgM Antibody (7U224) can be used in WB,IHC,IP.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:1000-5000; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundImmunoglobulin M (IgM) is the largest circulating antibody molecule in humans. It consists of a heavy chain (?-chain) and a light chain (κ- or λ-chain), as well as 5 base units and 10 binding sites, though it cannot bind all 10 simultaneously because of steric hindrance. IgM chain C refers to the constant region of the IgM heavy chain that is involved in immune regulation. IgM forms polymers by covalently linking multiple immunoglobulins together with disulfide bonds. It normally exists as a pentamer, but occasionally as a hexamer. Because of its polymeric nature, IgM has high avidity, and it is especially effective at complement activation. Due to its large size, IgM does not diffuse well, and it is found in the interstitium in very low amounts. IgM is mainly found in serum; however, because of the J chain, it is also important as a secretory immunoglobulin. IgM is the first immunoglobulin expressed by mature B cells, and it normally appears early in the course of an infection and does not reappear after further exposure.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 75 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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