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Anti-GLUR4 Antibody (5Y896)

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Catalog No. TMAB-06546

Anti-GLUR4 Antibody (5Y896) is a Rabbit antibody targeting GLUR4. Anti-GLUR4 Antibody (5Y896) can be used in WB,FCM.

Anti-GLUR4 Antibody (5Y896)

Anti-GLUR4 Antibody (5Y896)

😃Good
Catalog No. TMAB-06546
Anti-GLUR4 Antibody (5Y896) is a Rabbit antibody targeting GLUR4. Anti-GLUR4 Antibody (5Y896) can be used in WB,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1497-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-GLUR4 Antibody (5Y896) is a Rabbit antibody targeting GLUR4. Anti-GLUR4 Antibody (5Y896) can be used in WB,FCM.
Ig Type
IgG
Clone
5Y896
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein.Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Note=Interaction with CNIH2, CNIH3 and PRKCG promotes cell surface expression (By similarity).
Tissue SpecificityDetected in cerebellum (at protein level).
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundIonotropic glutamate receptor that functions as a ligand-gated cation channel, gated by L-glutamate and glutamatergic agonists such as alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), quisqualic acid, and kainic acid.
Antigen Details
Immunogen
A synthesized peptide: human GluR4
Antigen Species
Human
Gene Name
GRIA4
Gene ID
Protein Name
Glutamate receptor 4
Uniprot ID
Function
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Chemical Properties
Molecular WeightTheoretical: 101 kDa. Actual: 101 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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