Anti-GLUR4 Antibody (5Y896) is a Rabbit antibody targeting GLUR4. Anti-GLUR4 Antibody (5Y896) can be used in WB,FCM.

IgG

5Y896

Human,Mouse,Rat

1. Western blot analysis of SH-SY5Y cell lysate. Using GLUR4 (TMAB-06546) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.

WB: 1:500-2000; FCM: 1:50-100

Monoclonal

A synthesized peptide: human GluR4

Human

GRIA4

Glutamate receptor 4

Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.