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Anti-NOX2 Antibody (5H588)

😃Good
Catalog No. TMAB-09576

Anti-NOX2 Antibody (5H588) is a Rabbit antibody targeting NOX2. Anti-NOX2 Antibody (5H588) can be used in WB.

Anti-NOX2 Antibody (5H588)

Anti-NOX2 Antibody (5H588)

😃Good
Catalog No. TMAB-09576
Anti-NOX2 Antibody (5H588) is a Rabbit antibody targeting NOX2. Anti-NOX2 Antibody (5H588) can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
Anti-NOX2 Antibody (5H588) is a Rabbit antibody targeting NOX2. Anti-NOX2 Antibody (5H588) can be used in WB.
Ig Type
IgG
Clone
5H588
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-5000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundNOX2/gp91phox is a critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. It also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc. Defects in CYBB are a cause of X-linked chronic granulomatous disease (X-CGD). X-CGD is characterized by the failure of activated phagocytes to generate superoxide. Patients suffer from life-threatening bacterial/fungal infections.
Antigen Details
Immunogen
A synthesized peptide: human NOX2
Antigen Species
Human
Gene Name
CYBB
Gene ID
Protein Name
Cytochrome b-245 heavy chain
Uniprot ID
Function
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.
Chemical Properties
Molecular WeightTheoretical: 65 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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