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Anti-CYBB Antibody (6N434) (Synonyms: Superoxide-generating NADPH oxidase heavy chain subunit, p22 phagocyte B-...)
Catalog No. TMAC-02878 Copy Product Info
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Anti-CYBB Antibody (6N434) is a Rabbit antibody targeting CYBB. Anti-CYBB Antibody (6N434) can be used in WB.
Anti-CYBB Antibody (6N434)
Copy Product Info🥰Excellent
Catalog No. TMAC-02878
Synonyms Superoxide-generating NADPH oxidase heavy chain subunit, p22 phagocyte B-cytochrome, NOX2, Neutrophil cytochrome b 91 kDa polypeptide, NADPH oxidase 2, Heme-binding membrane glycoprotein gp91phox, gp91-phox, gp91-1, Cytochrome b-245 heavy chain, Cytochrome b(558) subunit beta (Cytochrome b558 subunit beta), CYBB, CGD91-phox
Anti-CYBB Antibody (6N434) is a Rabbit antibody targeting CYBB. Anti-CYBB Antibody (6N434) can be used in WB.
Anti-CYBB Antibody
(6N434)
(6N434)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-CYBB Antibody (6N434) is a Rabbit antibody targeting CYBB. Anti-CYBB Antibody (6N434) can be used in WB. |
| Synonyms | Superoxide-generating NADPH oxidase heavy chain subunit, p22 phagocyte B-cytochrome, NOX2, Neutrophil cytochrome b 91 kDa polypeptide, NADPH oxidase 2, Heme-binding membrane glycoprotein gp91phox, gp91-phox, gp91-1, Cytochrome b-245 heavy chain, Cytochrome b(558) subunit beta (Cytochrome b558 subunit beta), CYBB, CGD91-phox |
| Ig Type | IgG |
| Clone | 6N434 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of NOX2 on different lysates using anti-NOX2 antibody at 1/1,000 dilution. Positive control: Lane 1: MCF-7, Lane 2: THP-1, Lane 3: HepG2.  |
| Application | |
| Recommended Dose | WB: 1:1000-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Mox1 and the glycoprotein gp91-phox are largely related proteins that are essential components of the NADPH oxidase. The superoxide-generating NADPH oxidase is present in phagocytes, neuroepithelial bodies, vascular smooth muscle cells and endothelial cells. It includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane, where they associate with the flavocytochrome cytochrome b558 to form the active enzyme complex. The p22- and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. Mox1 and gp91 contain identical C-terminal sequence identity, yet they have distinct expression patterns. gp91-phox is expressed in eosinophils, neutro-phils, monocytes and B-lymphocytes, whereas Mox1 is predominantly detected in the colon, and low expression is also detected in the uterus and prostate. Mox1 is also upregulated in vascular smooth-muscle cells in response to PDGF stimulation, which collectively indicates that Mox1 may function analogously to gp91-phox, yet regulate the NADPH superoxide production in non-phagocytic cells. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 65 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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