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Anti-CD171/L1CAM Antibody (1Q622)
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Catalog No. TMAB-03881
Anti-CD171/L1CAM Antibody (1Q622) is a Rabbit antibody targeting CD171/L1CAM. Anti-CD171/L1CAM Antibody (1Q622) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-CD171/L1CAM Antibody (1Q622)
Anti-CD171/L1CAM Antibody (1Q622)
Copy Product Info😃Good
Catalog No. TMAB-03881
Anti-CD171/L1CAM Antibody (1Q622) is a Rabbit antibody targeting CD171/L1CAM. Anti-CD171/L1CAM Antibody (1Q622) can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-CD171/L1CAM Antibody (1Q622) is a Rabbit antibody targeting CD171/L1CAM. Anti-CD171/L1CAM Antibody (1Q622) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 1Q622 |
| Reactivity | Human |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded Human Colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD171/L1CAM Monoclonal Antibody, Unconjugated (TMAB-03881) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded Human Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD171/L1CAM Monoclonal Antibody, Unconjugated (TMAB-03881) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CD171/L1CAM Monoclonal Antibody, Unconjugated (TMAB-03881) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining. 4. 25 μg total protein per lane of various lysates (see on figure) probed with CD171/L1CAM monoclonal antibody, unconjugated (TMAB-03881) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. 5. Paraformaldehyde-fixed, paraffin embedded Human Cerebellum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with CD171/L1CAM Monoclonal Antibody, Unconjugated (TMAB-03881) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining. |
| Application | |
| Recommended Dose | WB: 1:1000-5000; IHC-P: 1:200-800; IHC-Fr: 1:200-800; IF: 1:200-800 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.02% Proclin300. |
| Concentration | 1mg/ml |
| Research Background | L1cam (L1 cell adhesion molecule isoform 1 precursor) is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq]. |
| Immunogen | A synthesized peptide: human NCAM L1 |
| Antigen Species | Human |
| Gene Name | L1CAM |
| Gene ID | |
| Protein Name | Neural cell adhesion molecule L1 |
| Uniprot ID | |
| Function | Cell adhesion molecule with an important role in the development of the nervous system. Involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Binds to axonin on neurons. |
| Molecular Weight | Theoretical: 138 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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