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Anti-FBXO5 Antibody (4G408)
😃Good
Catalog No. TMAB-05936
Anti-FBXO5 Antibody (4G408) is a Rabbit antibody targeting FBXO5. Anti-FBXO5 Antibody (4G408) can be used in IHC-P,IHC-Fr,IF,FCM.
Anti-FBXO5 Antibody (4G408)
Anti-FBXO5 Antibody (4G408)
😃Good
Catalog No. TMAB-05936
Anti-FBXO5 Antibody (4G408) is a Rabbit antibody targeting FBXO5. Anti-FBXO5 Antibody (4G408) can be used in IHC-P,IHC-Fr,IF,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-FBXO5 Antibody (4G408) is a Rabbit antibody targeting FBXO5. Anti-FBXO5 Antibody (4G408) can be used in IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG |
| Clone | 4G408 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Cytoplasm. Cytoplasm > cytoskeleton > spindle. In interphase, localizes in a punctate manner in the nucleus and cytoplasm with some perinuclear concentration. In mitotic cells, localizes throughout the cell, particularly at the spindle. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Regulator of APC activity during mitotic and meiotic cell cycle.During mitotic cell cycle plays a role as both substrate and inhibitor of APC-FZR1 complex.During G1 phase, plays a role as substrate of APC-FZR1 complex E3 ligase. |
| Immunogen | A synthesized peptide: human FBXO5 |
| Antigen Species | Human |
| Gene Name | FBXO5 |
| Gene ID | |
| Protein Name | F-box only protein 5 |
| Uniprot ID | |
| Function | Regulates progression through early mitosis by inhibiting the anaphase promoting complex/cyclosome (APC). Binds to the APC activators CDC20 and FZR1/CDH1 to prevent APC activation. Can also bind directly to the APC to inhibit substrate-binding. |
| Molecular Weight | Theoretical: 50 kDa. Actual: 56 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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