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Anti-BDNF Antibody (5C635)
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Catalog No. TMAH-00113
Alias Brain-Derived Neurotrophic Factor, BDNF, Abrineurin
Anti-BDNF Antibody (5C635) is an antibody targeting BDNF. Anti-BDNF Antibody (5C635) can be used in ELISA, WB.
Anti-BDNF Antibody (5C635)
Anti-BDNF Antibody (5C635)
😃Good
Catalog No. TMAH-00113Alias Brain-Derived Neurotrophic Factor, BDNF, Abrineurin
Anti-BDNF Antibody (5C635) is an antibody targeting BDNF. Anti-BDNF Antibody (5C635) can be used in ELISA, WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $208 | 7-10 days | |
| 100 μL | $349 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Rabbit Monoclonal Application: ELISA, WB Reactivity: Human, Mouse |
| Alias | Brain-Derived Neurotrophic Factor, BDNF, Abrineurin |
| Ig Type | Rabbit IgG |
| Clone | 5C635 |
| Reactivity | Human, Mouse |
| Verified Activity | Western Blot -Positive WB detected in: U87 whole cell lysate, U251 whole cell lysate, Mouse Brain tissue lysate -All lanes: BDNF antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 28 kDa -Observed band size: 28 kDa |
| Application | ELISA, WB |
| Recommended Dose | WB:1:500-1:2000. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Secreted.; [BDNF precursor form]: Secreted. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Important signaling molecule that activates signaling cascades downstream of NTRK2. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. Important signaling molecule that activates signaling cascades downstream of NTRK2. Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2. Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD). Binding to NGFR and SORCS2 promotes neuronal apoptosis. Promotes neuronal growth cone collapse. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human BDNF |
| Antigen Species | Human |
| Gene ID | 627 |
| Uniprot ID | |
| Biology Area | Neuroscience, Cardiovascular, Metabolism |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Sci Citations
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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