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Anti-Hsc70 Antibody (7V169)

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Catalog No. TMAB-07309

Anti-Hsc70 Antibody (7V169) is a Rabbit antibody targeting Hsc70. Anti-Hsc70 Antibody (7V169) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.

Anti-Hsc70 Antibody (7V169)

Anti-Hsc70 Antibody (7V169)

😃Good
Catalog No. TMAB-07309
Anti-Hsc70 Antibody (7V169) is a Rabbit antibody targeting Hsc70. Anti-Hsc70 Antibody (7V169) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Hsc70 Antibody (7V169) is a Rabbit antibody targeting Hsc70. Anti-Hsc70 Antibody (7V169) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
Ig Type
IgG
Clone
7V169
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Melanosome.
Tissue SpecificityUbiquitous.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundMolecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, chaperone-mediated autophagy, activation of proteolysis of misfolded proteins, formation and dissociation of protein complexes, and antigen presentation. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation.
Antigen Details
Immunogen
A synthesized peptide: human Hsc70
Antigen Species
Human
Gene Name
HSPA8
Gene ID
Protein Name
Heat shock cognate 71 kDa protein
Uniprot ID
Function
Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Isoform 2 may function as an endogenous inhibitory regulator of HSC70 by competing the co-chaperones.
Chemical Properties
Molecular WeightTheoretical: 71 kDa. Actual: 70 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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