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Anti-KIF2C Antibody (4R379)
Catalog No. TMAB-08045 Copy Product Info
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Anti-KIF2C Antibody (4R379) is a Rabbit antibody targeting KIF2C. Anti-KIF2C Antibody (4R379) can be used in WB,ICC/IF,FCM.
Anti-KIF2C Antibody (4R379)
Copy Product Info🥰Excellent
Catalog No. TMAB-08045
Anti-KIF2C Antibody (4R379) is a Rabbit antibody targeting KIF2C. Anti-KIF2C Antibody (4R379) can be used in WB,ICC/IF,FCM.
Anti-KIF2C Antibody
(4R379)
(4R379)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-KIF2C Antibody (4R379) is a Rabbit antibody targeting KIF2C. Anti-KIF2C Antibody (4R379) can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG |
| Clone | 4R379 |
| Reactivity | Human |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with KIF2C monoclonal antibody, unconjugated (TMAB-08045) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm > cytoskeleton. Nucleus. Chromosome > centromere. Chromosome > centromere > kinetochore. Associates with the microtubule network at the growing distal tip (the plus-end) of microtubules, probably through interaction with MTUS2/TIP150 and MAPRE1 (By similarity). Centromeric localization requires the presence of BUB1 and SGOL2. |
| Tissue Specificity | Expressed at high levels in thymus and testis, at low levels in small intestine, the mucosal lining of colon, and placenta, and at very low levels in spleen and ovary; expression is not detected in prostate, peripheral blood Leukocytes, heart, brain, lung, liver, skeletal muscle, kidney or pancreas. Isoform 2 is testis-specific. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells.Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis.Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment. |
| Immunogen | A synthesized peptide: human KIF2C |
| Antigen Species | Human |
| Gene Name | Kif2c |
| Gene ID | |
| Protein Name | Kinesin-like protein KIF2C |
| Uniprot ID | |
| Function | Promotes ATP-dependent removal of tubulin dimers from microtubules. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. |
| Molecular Weight | Theoretical: 81 kDa. Actual: 81 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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