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Anti-KIF2C Antibody (4R379)

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Catalog No. TMAB-08045

Anti-KIF2C Antibody (4R379) is a Rabbit antibody targeting KIF2C. Anti-KIF2C Antibody (4R379) can be used in WB,ICC/IF,FCM.

Anti-KIF2C Antibody (4R379)

Anti-KIF2C Antibody (4R379)

😃Good
Catalog No. TMAB-08045
Anti-KIF2C Antibody (4R379) is a Rabbit antibody targeting KIF2C. Anti-KIF2C Antibody (4R379) can be used in WB,ICC/IF,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-KIF2C Antibody (4R379) is a Rabbit antibody targeting KIF2C. Anti-KIF2C Antibody (4R379) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
Clone
4R379
Reactivity
Human
Application
WB
ICC/IF
FCM
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm > cytoskeleton. Nucleus. Chromosome > centromere. Chromosome > centromere > kinetochore. Associates with the microtubule network at the growing distal tip (the plus-end) of microtubules, probably through interaction with MTUS2/TIP150 and MAPRE1 (By similarity). Centromeric localization requires the presence of BUB1 and SGOL2.
Tissue SpecificityExpressed at high levels in thymus and testis, at low levels in small intestine, the mucosal lining of colon, and placenta, and at very low levels in spleen and ovary; expression is not detected in prostate, peripheral blood Leukocytes, heart, brain, lung, liver, skeletal muscle, kidney or pancreas. Isoform 2 is testis-specific.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundIn complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells.Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis.Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment.
Antigen Details
Immunogen
A synthesized peptide: human KIF2C
Antigen Species
Human
Gene Name
Kif2c
Gene ID
11004
Protein Name
Kinesin-like protein KIF2C
Uniprot ID
Q99661
Function
Promotes ATP-dependent removal of tubulin dimers from microtubules. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis.
Chemical Properties
Molecular WeightTheoretical: 81 kDa. Actual: 81 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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