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Anti-RNF14 Antibody (7W287)
Catalog No. TMAB-12294 Copy Product Info
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Anti-RNF14 Antibody (7W287) is a Rabbit antibody targeting RNF14. Anti-RNF14 Antibody (7W287) can be used in WB.
Anti-RNF14 Antibody (7W287)
Copy Product Info🥰Excellent
Catalog No. TMAB-12294
Anti-RNF14 Antibody (7W287) is a Rabbit antibody targeting RNF14. Anti-RNF14 Antibody (7W287) can be used in WB.
Anti-RNF14 Antibody
(7W287)
(7W287)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-RNF14 Antibody (7W287) is a Rabbit antibody targeting RNF14. Anti-RNF14 Antibody (7W287) can be used in WB. |
| Ig Type | IgG |
| Clone | 7W287 |
| Reactivity | Human (predicted:Mouse,Rat) |
| Verified Activity | 25 ug total protein per lane of various lysates (see on figure) probed with RNF14 monoclonal antibody, unconjugated (TMAB-12294) at 1: 1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. |
| Tissue Specificity | Widely expressed. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | E3 ubiquitin-protein ligase that plays a key role in the RNF14-RNF25 translation quality control pathway, a pathway that takes place when a ribosome has stalled during translation, and which promotes ubiquitination and degradation of translation factors on stalled ribosomes.Recruited to stalled ribosomes by the ribosome collision sensor GCN1 and mediates 'Lys-6'-linked ubiquitination of target proteins, leading to their degradation. |
| Immunogen | A synthesized peptide: human RNF14 |
| Antigen Species | Human |
| Gene Name | RNF14 |
| Gene ID | |
| Protein Name | E3 ubiquitin-protein ligase RNF14 |
| Uniprot ID | |
| Function | Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription. |
| Molecular Weight | Theoretical: 54 kDa. Actual: 54 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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