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Anti-Elongin B Antibody (6A534)
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Catalog No. TMAB-05544 Copy Product Info
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Anti-Elongin B Antibody (6A534) is a Rabbit antibody targeting Elongin B. Anti-Elongin B Antibody (6A534) can be used in WB.
Anti-Elongin B Antibody
(6A534)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 µL | $151 | 7-10 days | 7-10 days | |
| 50 µL | $264 | 7-10 days | 7-10 days | |
| 100 µL | $471 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Elongin B Antibody (6A534) is a Rabbit antibody targeting Elongin B. Anti-Elongin B Antibody (6A534) can be used in WB. |
| Ig Type | IgG |
| Clone | 6A534 |
| Reactivity | Human |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with Elongin B monoclonal antibody, unconjugated (TMAB-05544) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex) |
| Immunogen | A synthesized peptide: human Elongin B |
| Antigen Species | Human |
| Gene Name | ELOB |
| Gene ID | |
| Protein Name | Elongin-B |
| Uniprot ID | |
| Function | SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
The elongin BC complex seems to be involved as an adapter protein in the proteasomal degradation of target proteins via different E3 ubiquitin ligase complexes, including the von Hippel-Lindau ubiquitination complex CBC(VHL). By binding to BC-box motifs it seems to link target recruitment subunits, like VHL and members of the SOCS box family, to Cullin/RBX1 modules that activate E2 ubiquitination enzymes. |
| Molecular Weight | Theoretical: 13 kDa. Actual: 15 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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