Anti-Elongin B Antibody (6A534) is a Rabbit antibody targeting Elongin B. Anti-Elongin B Antibody (6A534) can be used in WB.

IgG

6A534

Human

25 μg total protein per lane of various lysates (see on figure) probed with Elongin B monoclonal antibody, unconjugated (TMAB-05544) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.

WB: 1:500-2000

Monoclonal

A synthesized peptide: human Elongin B

Human

ELOB

Elongin-B

SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
The elongin BC complex seems to be involved as an adapter protein in the proteasomal degradation of target proteins via different E3 ubiquitin ligase complexes, including the von Hippel-Lindau ubiquitination complex CBC(VHL). By binding to BC-box motifs it seems to link target recruitment subunits, like VHL and members of the SOCS box family, to Cullin/RBX1 modules that activate E2 ubiquitination enzymes.