Latent GDF-8 Protein, Mouse, Recombinant (His)

Name: Latent GDF-8 Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPK-01703
Rating: 4.5 (1 reviews)

(Synonyms: myostatin, Gdf8, Cmpt) Copy Product Info

Synonyms: myostatin, Gdf8, Cmpt

Catalog No. TMPK-01703 Copy Product Info

Latent GDF-8 Protein, Mouse, Recombinant (His) is expressed in HEK293 Cells. The accession number is O08689.

Customer service consultation

Pack Size	Price	USA Stock	Global Stock
5 µg	$108	7-10 days	7-10 days
10 µg	$169	7-10 days	7-10 days
20 µg	$267	7-10 days	7-10 days
50 µg	$488	7-10 days	7-10 days
100 µg	$776	7-10 days	7-10 days
200 µg	$1,230	7-10 days	7-10 days
500 µg	$2,290	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

Bioactivity

Bioactivity	Immobilized Mouse Latent GDF-8, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Apitegromab, hFc Tag with the EC50 of 32.6 ng/ml determined by ELISA (QC Test).
Description	Latent GDF-8 Protein, Mouse, Recombinant (His) is expressed in HEK293 Cells. The accession number is O08689.
Species	Mouse
Expression System	HEK293 Cells
Tag	N-His
Accession Number	O08689
Construction	Asn25-Ser376
Protein Purity	> 95% as determined by Bis-Tris PAGE; > 90% as determined by HPLC
Endotoxin	< 0.1 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	myostatin, Gdf8, Cmpt
Research Background	Growth/differentiation factor 8 (GDF8), or myostatin, negatively regulates muscle mass. GDF8 is held in a latent state through interactions with its N-terminal prodomain. GDF8, like numerous TGF-β family members, is a disulfidelinked dimer that is synthesized as a precursor protein which requires cleavage by a furin-like protease to yield an N-terminal prodomain and a C-terminal mature, signaling domain.

Chemical Properties

Molecular Weight

41.18 kDa (Predicted); 14 kDa and 32-38 kDa (Reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.