Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-ATG16L1 Antibody (3G388)
Catalog No. TMAB-02913 Copy Product Info
🥰Excellent
Anti-ATG16L1 Antibody (3G388) is a Rabbit antibody targeting ATG16L1. Anti-ATG16L1 Antibody (3G388) can be used in WB.
Anti-ATG16L1 Antibody (3G388)
Copy Product Info🥰Excellent
Catalog No. TMAB-02913
Anti-ATG16L1 Antibody (3G388) is a Rabbit antibody targeting ATG16L1. Anti-ATG16L1 Antibody (3G388) can be used in WB.
Anti-ATG16L1 Antibody
(3G388)
(3G388)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-ATG16L1 Antibody (3G388) is a Rabbit antibody targeting ATG16L1. Anti-ATG16L1 Antibody (3G388) can be used in WB. |
| Ig Type | IgG |
| Clone | 3G388 |
| Reactivity | Human |
| Verified Activity | Sample: Lane 1: Human PANC-1 cell lysates Lane 2: Human Jurkat cell lysates Lane 3: Human HeLa cell lysates Lane 4: Human HepG2 cell lysates Primary: Anti-ATG16L1 (TMAB-02913) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 68 kDa Observed band size: 66,68 kDa |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm |
| Tissue Specificity | Expressed in right hemisphere of cerebellum and 147 other tissues |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 50mM Tris-Glycine (pH7.4), 0.15M NaCl, 40% Glycerol, 0.02% Proclin300 and 0.05% BSA. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010] |
| Immunogen | KLH conjugated synthetic peptide: human ATG16L1 |
| Antigen Species | Human |
| Gene Name | ATG16L1 |
| Gene ID | |
| Protein Name | Autophagy-related protein 16-1 |
| Uniprot ID | |
| Function | Plays an essential role in both canonical and non-canonical autophagy: interacts with ATG12-ATG5 to mediate the lipidation to ATG8 family proteins (MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAPL1, GABARAPL2 and GABARAP) (PubMed:23376921, PubMed:23392225, PubMed:29317426, PubMed:30778222, PubMed:33909989, PubMed:24553140, PubMed:24954904, PubMed:27273576).Acts as a molecular hub, coordinating autophagy pathways via distinct domains that support either canonical or non-canonical signaling (PubMed:29317426, PubMed:30778222).During canonical autophagy, interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to ATG8 proteins, to produce a membrane-bound activated form of ATG8 (PubMed:23376921, PubMed:23392225, PubMed:24553140, PubMed:24954904, PubMed:27273576).Thereby, controls the elongation of the nascent autophagosomal membrane (PubMed:23376921, PubMed:23392225, PubMed:24553140, PubMed:24954904, PubMed:27273576).Also involved in non-canonical autophagy, a parallel pathway involving conjugation of ATG8 proteins to single membranes at endolysosomal compartments, probably by catalyzing conjugation of phosphatidylserine (PS) to ATG8 (PubMed:33909989).Non-canonical autophagy plays a key role in epithelial cells to limit lethal infection by influenza A (IAV) virus (By similarity).Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production (PubMed:22749352, PubMed:25645662).Negatively regulates NOD1- and NOD2-driven inflammatory cytokine response (PubMed:24238340).Instead, promotes with NOD2 an autophagy-dependent antibacterial pathway (PubMed:20637199).Plays a role in regulating morphology and function of Paneth cell (PubMed:18849966). |
| Molecular Weight | Theoretical: 68 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
Preview
Related Tags: buy Anti-ATG16L1 Antibody (3G388) | purchase Anti-ATG16L1 Antibody (3G388) | Anti-ATG16L1 Antibody (3G388) cost | order Anti-ATG16L1 Antibody (3G388) | Anti-ATG16L1 Antibody (3G388) molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.