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Anti-LILRA4/CD85g Antibody (3H551) (Synonyms: MGC129597, LILRA4, ILT7MGC129598, ILT-7, ILT7, CD85g)

Catalog No. TMAH-00698 Copy Product Info
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Anti-LILRA4/CD85g Antibody (3H551) is an antibody targeting LILRA4/CD85g. Anti-LILRA4/CD85g Antibody (3H551) can be used in ELISA,IHC,WB.

Anti-LILRA4/CD85g Antibody (3H551)

Copy Product Info
🥰Excellent
Catalog No. TMAH-00698
Synonyms MGC129597, LILRA4, ILT7MGC129598, ILT-7, ILT7, CD85g

Anti-LILRA4/CD85g Antibody (3H551) is an antibody targeting LILRA4/CD85g. Anti-LILRA4/CD85g Antibody (3H551) can be used in ELISA,IHC,WB.

Anti-LILRA4/CD85g Antibody
(3H551)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2097-10 days7-10 days
100 μL$3477-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-LILRA4/CD85g Antibody (3H551) is an antibody targeting LILRA4/CD85g. Anti-LILRA4/CD85g Antibody (3H551) can be used in ELISA,IHC,WB.
SynonymsMGC129597, LILRA4, ILT7MGC129598, ILT-7, ILT7, CD85g
Ig Type
hIgG1
Clone
3H551
Reactivity
Human
Verified Activity
1. Western Blot
-Positive WB detected in:Hela whole cell lysate (20µg), HpeG2 whole cell lysate (20µg), Jurkat whole cell lysate (20µg), K562 whole cell lysate (20µg)
-All lanes: LILRA4 antibody at 1:1000
-Secondary: Goat polyclonal to human IgG at 1/40000 dilution
-Predicted band size:55.18, 47.81 kDa
-Observed band size:50 kDa
-Exposure time:20s
2. IHC image of TMAH-00698 diluted at 1:100 and staining in paraffin-embedded human skin tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB.
Application
Recommended Dose
WB:1:500-1:2000; IHC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationCell membrane; Single-pass type I membrane protein.
Tissue SpecificityDetected on plasmacytoid dendritic cells (at protein level). Detected on plasmacytoid dendritic cells, but not on monocytes or B cells.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPreservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4.
Research BackgroundFunctions coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G. Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades. Down-regulates interferon production in response to interaction with BST2 on HIV-1 infected cells. Activates a signaling cascade in complex with FCER1G that results in phosphorylation of Src family and Syk kinases and thereby triggers mobilization of intracellular Ca(2+). Does not interfere with the differentiation of plasmacytoid dendritic cells into antigen-presenting cells.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human LILRA4 Protein
Antigen Species
Human
Gene Name
LILRA4
Gene ID
Uniprot ID
Biology Area
Immunology
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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