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Synonyms: interleukin 1, β, interleukin 1, beta, interleukin 1 beta, IL-1β, IL1F2, IL1-BETA, IL-1beta, IL1beta, Il-1b, IL1B, IL-1 β, IL-1


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $108 | 7-10 days | 7-10 days | |
| 10 µg | $169 | 7-10 days | 7-10 days | |
| 20 µg | $267 | 7-10 days | 7-10 days | |
| 50 µg | $488 | 7-10 days | 7-10 days | |
| 100 µg | $776 | 7-10 days | 7-10 days | |
| 200 µg | $1,230 | 7-10 days | 7-10 days | |
| 500 µg | $2,290 | 7-10 days | 7-10 days |
| Bioactivity | Immobilized Biotinylated Mouse IL-1 Beta, His Tag at 2 μg/ml (100 μl/well) on the streptavidin precoated plate (5 μg/ml). Dose response curve for Human IL-1 R2, hFc Tag with the EC50 of 25.4 ng/ml determined by ELISA (QC Test). |
| Description | IL-1 beta/IL-1F2 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in E. coli. The accession number is P10749. |
| Species | Mouse |
| Expression System | E. coli |
| Tag | N-His-Avi |
| Accession Number | P10749 |
| Construction | Val118-Ser269 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | interleukin 1, β, interleukin 1, beta, interleukin 1 beta, IL-1β, IL1F2, IL1-BETA, IL-1beta, IL1beta, Il-1b, IL1B, IL-1 β, IL-1 |
| Research Background | Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells. |
| Molecular Weight | 20.30 kDa (Predicted); 20-25 kDa (Reducing condition) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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