Measured by its esterase activity. The specific activity is > 40 pmol/min/µg. (QC Test)

Carbonic Anhydrase 12 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is O43570-1.

Human

HEK293 Cells

Ala25-Ser301

> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues. Carbonic anhydrase XII (CA XII) is a key mediator of several signaling pathways that are involved in cancer development.