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Oncostatin M/OSM Protein, Cynomolgus, Recombinant (His)

(Synonyms: OSM, Oncostatin M) Copy Product Info

Synonyms: OSM, Oncostatin M

Catalog No. TMPK-01995 Copy Product Info
Oncostatin M/OSM Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 Cells. The accession number is XP_045219762.1.
Oncostatin M/OSM Protein, Cynomolgus, Recombinant (His)
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Pack SizePriceUSA StockGlobal StockQuantity
10 µg$1137-10 days7-10 days
20 µg$1757-10 days7-10 days
50 µg$3167-10 days7-10 days
100 µg$4907-10 days7-10 days
200 µg$7937-10 days7-10 days
500 µg$1,4707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Human LIF R, hFc Tag captured on CM5 Chip via Protein A can bind Cynomolgus OSM, His Tag with an affinity constant of 1.31 μM as determined in SPR assay (Biacore T200).
Description
Oncostatin M/OSM Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 Cells. The accession number is XP_045219762.1.
Species
Cynomolgus
Expression System
HEK293 Cells
TagC-His
Accession NumberXP_045219762.1
ConstructionAla27-Arg221
Protein Purity
> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Endotoxin< 1 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in PBS (pH 7.4).
SynonymsOSM, Oncostatin M
Research Background
OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
Chemical Properties
Molecular Weight23.31 kDa (Predicted); 27-50 kDa (Reducing condition, due to glycosylation)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: Oncostatin M/OSM Protein, Cynomolgus, Recombinant (His) chemical structure | Oncostatin M/OSM Protein, Cynomolgus, Recombinant (His) molecular weight